CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026333
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Receptor-type tyrosine-protein phosphatase kappa 
Protein Synonyms/Alias
  
Gene Name
 PTPRK 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
731QCVRIATKAAATEEPubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1458 AA 
Protein Sequence
MDTTAAAALP AFVALLLLSP WPLLGSAQGQ FSAGGCTFDD GPGACDYHQD LYDDFEWVHV 60
SAQEPHYLPP EMPQGSYMIV DSSDHDPGEK ARLQLPTMKE NDTHCIDFSY LLYSQKGLNP 120
GTLNILVRVN KGPLANPIWN VTGFTGRDWL RAELAVSTFW PNEYQVIFEA EVSGGRSGYI 180
AIDDIQVLSY PCDKSPHFLR LGDVEVNAGQ NATFQCIATG RDAVHNKLWL QRRNGEDIPV 240
AQTKNINHRR FAASFRLQEV TKTDQDLYRC VTQSERGSGV SNFAQLIVRE PPRPIAPPQL 300
LGVGPTYLLI QLNANSIIGD GPIILKEVEY RMTSGSWTET HAVNAPTYKL WHLDPDTEYE 360
IRVLLTRPGE GGTGLPGPPL ITRTKCAEPM RTPKTLKIAE IQARRIAVDW ESLGYNITRC 420
HTFNVTICYH YFRGHNESKA DCLDMDPKAP QHVVNHLPPY TNVSLKMILT NPEGRKESEE 480
TIIQTDEDVP GPVPVKSLQG TSFENKIFLN WKEPLDPNGI ITQYEISYSS IRSFDPAVPV 540
AGPPQTVSNL WNSTHHVFMH LHPGTTYQFF IRASTVKGFG PATAINVTTN ISAPTLPDYE 600
GVDASLNETA TTITVLLRPA QAKGAPISAY QIVVEELHPH RTKREAGAME CYQVPVTYQN 660
AMSGGAPYYF AAELPPGNLP EPAPFTVGDN RTYQGFWNPP LAPRKGYNIY FQAMSSVEKE 720
TKTQCVRIAT KAAATEEPEV IPDPAKQTDR VVKIAGISAG ILVFILLLLV VILIVKKSKL 780
AKKRKDAMGN TRQEMTHMVN AMDRSYADQS TLHAEDPLSI TFMDQHNFSP RLPNDPLVPT 840
AVLDENHSAT AESSRLLDVP RYLCEGTESP YQTGQLHPAI RVADLLQHIN LMKTSDSYGF 900
KEEYESFFEG QSASWDVAKK DQNRAKNRYG NIIAYDHSRV ILQPVEDDPS SDYINANYID 960
IWLYRDGYQR PSHYIATQGP VHETVYDFWR MIWQEQSACI VMVTNLVEVG RVKCYKYWPD 1020
DTEVYGDFKV TCVEMEPLAE YVVRTFTLER RGYNEIREVK QFHFTGWPDH GVPYHATGLL 1080
SFIRRVKLSN PPSAGPIVVH CSAGAGRTGC YIVIDIMLDM AEREGVVDIY NCVKALRSRR 1140
INMVQTEEQY IFIHDAILEA CLCGETAIPV CEFKAAYFDM IRIDSQTNSS HLKDEFQTLN 1200
SVTPRLQAED CSIACLPRNH DKNRFMDMLP PDRCLPFLIT IDGESSNYIN AALMDSYRQP 1260
AAFIVTQYPL PNTVKDFWRL VYDYGCTSIV MLNEVDLSQG CPQYWPEEGM LRYGPIQVEC 1320
MSCSMDCDVI NRIFRICNLT RPQEGYLMVQ QFQYLGWASH REVPGSKRSF LKLILQVEKW 1380
QEECEEGEGR TIIHCLNGGG RSGMFCAIGI VVEMVKRQNV VDVFHAVKTL RNSKPNMVEA 1440
PEQYRFCYDV ALEYLESS 1458 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
 GO:0035335; P:peptidyl-tyrosine dephosphorylation; IEA:GOC. 
Interpro
 IPR008985; ConA-like_lec_gl_sf.
 IPR003961; Fibronectin_type3.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003599; Ig_sub.
 IPR000998; MAM_dom.
 IPR000387; Tyr/Dual-sp_Pase.
 IPR016130; Tyr_Pase_AS.
 IPR000242; Tyr_Pase_rcpt/non-rcpt. 
Pfam
 PF00041; fn3
 PF00629; MAM
 PF00102; Y_phosphatase 
SMART
 SM00060; FN3
 SM00409; IG
 SM00137; MAM
 SM00194; PTPc 
PROSITE
 PS50853; FN3
 PS50835; IG_LIKE
 PS00740; MAM_1
 PS50060; MAM_2
 PS00383; TYR_PHOSPHATASE_1
 PS50056; TYR_PHOSPHATASE_2
 PS50055; TYR_PHOSPHATASE_PTP 
PRINTS
 PR00020; MAMDOMAIN.
 PR00700; PRTYPHPHTASE.