CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039595
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Calcium-binding mitochondrial carrier protein Aralar2 
Protein Synonyms/Alias
  
Gene Name
 SLC25A13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
245VYPIDLVKTRMQNQRubiquitination[1]
300VAPEKAIKLTVNDFVubiquitination[2]
376LGFFGIYKGAKACFLubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 567 AA 
Protein Sequence
MEDVKQVFGQ TTIHQHIPFN WDSEFVQLHF GKERKRHLTY AEFTQFLLEI QLEHAKQAFV 60
QRDNARTGRV TAIDFRDIMV TIRPHVLTPF VEECLVAAAG GTTSHQVSFS YFNGFNSLLN 120
NMELIRKIYS TLAGTRKDVE VTKEEFVLAA QKFGQVTPME VDILFQLADL YEPRGRMTLA 180
DIERIAPLEE GTLPFNLAEA QRQKASGDSA RPVLLQVAES AYRFGLGSVA GAVGATAVYP 240
IDLVKTRMQN QRSTGSFVGE LMYKNSFDCF KKVLRYEGFF GLYRGLLPQL LGVAPEKAIK 300
LTVNDFVRDK FMHKDGSVPL AAEILAGGCA GGSQVIFTNP LEIVKIRLQV AGEITTGPRV 360
SALSVVRDLG FFGIYKGAKA CFLRDIPFSA IYFPCYAHVK ASFANEDGQV SPGSLLLAGA 420
IAGMPAASLV TPADVIKTRL QVAARAGQTT YSGVIDCFRK ILREEGPKAL WKGAGARVFR 480
SSPQFGVTLL TYELLQRWFY IDFGGVKPMG SEPVPKSRIN LPAPNPDHVG GYKLAVATFA 540
GIENKFGLYL PLFKPSVSTS KAIGGGP 567 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0055085; P:transmembrane transport; IEA:InterPro. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR002067; Mit_carrier.
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS
 PR00926; MITOCARRIER.