UniProt Accession

 G6B_HUMAN; O95866; A2BEZ1; A2BEZ2; A2BEZ3; A2BEZ4; A2BEZ5; B0UXC4; B0UXC7; B0UXC8; B0V024; B0V026; Q14CK2; Q96A86; Q96A87; Q96A88; Q96A89; Q96A90; Q96A91 

Genbank Protein ID

 AJ292259; AJ292260; AJ292261; AJ292262; AJ292263; AJ292264; AJ292265; AF129756; BA000025; AL670886; AL670886; AL670886; AL670886; AL670886; AL662899; AL662899; AL662899; AL662899; AL662899; BX248244; BX248244; BX248244; BX248244; BX248244; AL844216; AL844216; AL844216; AL844216; AL844216; CR354443; CR354443; CR354443; CR936239; CR936239; CR936239; CR936239; CR759787; CR759787; CR759787; CR759787; CH471081; CH471081; CH471081; CH471081; BC113719; BC113721 

Genbank Nucleotide ID

 CAC83497.1; CAC83496.1; CAC83498.1; CAC83502.1; CAC83499.1; CAC83500.1; CAC83501.1; AAD18075.1; BAB63378.1; CAI17813.2; CAI17814.2; CAI17815.1; CAI17816.2; CAI17818.2; CAI18406.2; CAI18407.2; CAI18408.1; CAI18409.2; CAI18412.2; CAM26092.1; CAM26093.1; CAM26094.1; CAM26095.1; CAM26096.1; CAM45767.1; CAM45768.1; CAM45769.1; CAM45770.1; CAM45771.1; CAQ07017.1; CAQ07020.1; CAQ07021.1; CAQ08890.1; CAQ08892.1; CAQ08893.1; CAQ08894.1; CAQ10105.1; CAQ10107.1; CAQ10108.1; CAQ10109.1; EAX03493.1; EAX03494.1; EAX03497.1; EAX03498.1; AAI13720.1; AAI13722.1 

Protein Name

 Protein G6b 

Protein Synonyms/Alias

  

Gene Name

 G6B 

Gene Synonyms/Alias

 C6orf25 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
130	LGDRTYCKAPGPTHA	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

 Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart. 

Sequence Annotation

 MOD_RES 211 211 Phosphotyrosine.
 CARBOHYD 32 32 N-linked (GlcNAc...) (Potential).  

Keyword

 Alternative splicing; Cell membrane; Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Heparin-binding; Membrane; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 241 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IDA:UniProtKB.
 GO:0008201; F:heparin binding; IEA:UniProtKB-KW. 

Interpro

 IPR003599; Ig_sub. 

Pfam

  

SMART

 SM00409; IG 

PROSITE

  

PRINTS