CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038530
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 
Protein Synonyms/Alias
  
Gene Name
 Usp31 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
417NNNLNHLKFGLDHHRacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1344 AA 
Protein Sequence
MSKVTAPGPG PPVAAGGKEK RSFSKRLFRS GRAGGGGGAG GPGPAAPSSP SSARSVGSFM 60
SRVLKTLSTL SHLSSEGAAP DRGGLRSCFP PGPASAPTPP PCPPPPASPA PPACASEPVP 120
GVAGLRNHGN TCFMNATLQC LSNTELFAEY LALGQYRAGR PEPEPESEQP AGRGPHGQGE 180
VTEQLAHLVR ALWTLEYTPQ HSRDFKSIVS KNALQYRGNS QHDAQEFLLW LLDRVHEDLN 240
HAVKQSGQPP LKPPSETDMM PEGPFPVCST FVQELFQAQY RSSLTCPHCQ KQSNTFDPFL 300
CISLPIPLPH TRPLYVTVVY QGKCSHCMRI GVAVPLSGTV ARLREAVSME TKIPTDQIVL 360
TEMYYDGFHR SFSDTDDLET VHESDCIFAF ETPEIFRPEG ILSQRGIHLN NNLNHLKFGL 420
DHHRLSSPAP TAAKQGRVDL PTRVASDKIV LLVCNRACTG QQGKRFGLPF VLHLEKTVAW 480
DLLQKEILEK MKYFLRPTVS IQVCPFSLRV VSVVGITYLL PQEEQPLCHP TVERALKSCG 540
PGGTAHVKLV VEWDKETKDF LFVNTEDEYI PDAESVRLQK EQHHQPQTCT LSQCFQLYTK 600
EERLAPDDAW RCPHCKQLQQ GSITLSLWTL PDVLIIHLKR FRQEGDRRMK LQNMVKFPLT 660
GLDMTPHVVK RSQSSWSLPS HWSPWRRPYG LGRDPEDYIY DLYAVCNHHG TMQGGHYTAY 720
CKNSVDGLWY CFDDSDVQQL SEDEVCTQTA YILFYQRRTA IPSWSANSSV AGSTSSSLCE 780
HWVSRLPGSK QASVTSAASS RRTSLASLSE SVEMTGERSE DDGGFSTRPF VRSVQRQSLS 840
SRSSVTSPLA VNENCMRPSW SLSAKLQMRS SSPSRFSGDS PIHGSASTLE RIGEAGDDKV 900
SISCFGSLRN LSGSHQEPSD SHNRREHKAV GRAPLAVMEG VFKDDSDPGK LNSSVVDTPS 960
KNRAQGDHLP PVSDPFDNNN QIAYVDQSDS VDSSPVKEVK PPSHSDSLTK KPESTTKSSP 1020
SSKGTSEPEK NMRKGRPALA SQESSLSSPS PSSPVPVKVS MKPARCRSKA DSSRTSGRHS 1080
SSSSTQPKKE SSPRSQESMS SPSPQKQKSA SAFTYSSSSI SAKKAPSPVT RGPFPSGKSR 1140
TSDRSLSREG SRQSLGSDRA SVTSTSTSKP SSPRVNQARA GDNRVDGKHV RSSSMASLRS 1200
PSTSVRSGLK RDSKSEDKGL SFFKSALRQK ETRRSTDLGK TTLLSKKAGG SSVKSVSKNT 1260
ADDKTEKGHQ PPGSQQPNTN AVGKEQLVSK DPAKHSLLSA RRSKSSQLDS GAPLSPSSRS 1320
TTEKGSKKLS SSMQTSARPS QKPQ 1344 
Gene Ontology
 GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19. 
Pfam
 PF00443; UCH 
SMART
  
PROSITE
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3 
PRINTS