Tag | Content |
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CPLM ID | CPLM-005116 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Proteasome subunit alpha type-7-1 |
Protein Synonyms/Alias | PROS-Dm28.1; Proteasome 28 kDa subunit 1 |
Gene Name | Pros28.1 |
Gene Synonyms/Alias | PROS-28.1; CG3422 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
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50 | VVLGVEKKSVAQLQE | acetylation | [1] |
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Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
Sequence Annotation | MOD_RES 177 177 Phosphoserine. |
Keyword | Complete proteome; Cytoplasm; Hydrolase; Nucleus; Phosphoprotein; Protease; Proteasome; Reference proteome; Threonine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 249 AA |
Protein Sequence | MSSRYDRAVT IFSPDGHLLQ VEYAQEAVRK GSTAVGVRGA NCVVLGVEKK SVAQLQEDRK 60 VRKICMLDNH VVMAFAGLTA DARIMINRAQ VECQSHRLNV EDPVTLEYIT RFIAQLKQKY 120 TQSNGRRPFG ISCLIGGFDA DGSAHLFQTE PSGIFYEYKA NATGRSAKVV REFFEKSYRE 180 EEVANEHGAV KLAIRALLEV AQSGQNNLEV AIMENGKPLK MLDTDVITDY VKIIEKEKEE 240 ELEKKKQKK 249 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0005875; C:microtubule associated complex; IDA:FlyBase. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0005839; C:proteasome core complex; IDA:FlyBase. GO:0019773; C:proteasome core complex, alpha-subunit complex; IEA:InterPro. GO:0004298; F:threonine-type endopeptidase activity; IEA:UniProtKB-KW. GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:FlyBase. GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. |
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PROSITE | |
PRINTS | |