UniProt Accession

 TALDO_RAT; Q9EQS0; Q6PCV1 

Genbank Protein ID

 AF069306; BC059126 

Genbank Nucleotide ID

 AAG43169.1; AAH59126.1 

Protein Name

 Transaldolase 

Protein Synonyms/Alias

  

Gene Name

 Taldo1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
7	*MSGSPVKRQRMESA	acetylation	[1]
130	RRIIELYKEAGISKD	acetylation	[1]
130	RRIIELYKEAGISKD	ubiquitination	[2]
136	YKEAGISKDRILIKL	acetylation	[1]
203	WHVANTDKKSYEPQE	acetylation	[1]
219	PGVKSVTKIYNYYKK	acetylation	[1]
219	PGVKSVTKIYNYYKK	ubiquitination	[2]
258	DFLTISPKLLGELLK	acetylation	[1]
265	KLLGELLKDSSKLAP	acetylation	[1]
269	ELLKDSSKLAPTLSV	acetylation	[1]
269	ELLKDSSKLAPTLSV	ubiquitination	[2]
277	LAPTLSVKAAQTSDL	ubiquitination	[2]
286	AQTSDLEKIHLDEKA	acetylation	[1]
292	EKIHLDEKAFRWLHN	acetylation	[1]
307	EDQMAVEKLSDGIRK	acetylation	[1]
314	KLSDGIRKFAADAIK	acetylation	[1]
321	KFAADAIKLERMLTE	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity). 

Sequence Annotation

 ACT_SITE 142 142 Schiff-base intermediate with substrate
 MOD_RES 219 219 N6-acetyllysine (By similarity).
 MOD_RES 269 269 N6-acetyllysine (By similarity).
 MOD_RES 286 286 N6-acetyllysine (By similarity).
 MOD_RES 321 321 N6-acetyllysine (By similarity).  

Keyword

 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Pentose shunt; Reference proteome; Schiff base; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 337 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:RGD.
 GO:0043231; C:intracellular membrane-bounded organelle; IDA:RGD.
 GO:0048029; F:monosaccharide binding; IDA:RGD.
 GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; IDA:RGD.
 GO:0006002; P:fructose 6-phosphate metabolic process; IDA:RGD.
 GO:0019682; P:glyceraldehyde-3-phosphate metabolic process; IDA:RGD.
 GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IDA:RGD. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR001585; Transaldolase.
 IPR004730; Transaldolase_1.
 IPR018225; Transaldolase_AS. 

Pfam

 PF00923; Transaldolase 

SMART

  

PROSITE

 PS01054; TRANSALDOLASE_1
 PS00958; TRANSALDOLASE_2 

PRINTS