CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020493
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leucine-zipper-like transcriptional regulator 1 
Protein Synonyms/Alias
 LZTR-1 
Gene Name
 Lztr1 
Gene Synonyms/Alias
 Tcfl2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
372DFGTTSAKQPVHLASubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probable transcriptional regulator that may play a crucial role in embryogenesis (By similarity). 
Sequence Annotation
 REPEAT 76 125 Kelch 1.
 REPEAT 127 182 Kelch 2.
 REPEAT 184 235 Kelch 3.
 REPEAT 236 282 Kelch 4.
 REPEAT 292 338 Kelch 5.
 REPEAT 396 447 Kelch 6.
 DOMAIN 440 534 BTB 1.
 DOMAIN 664 733 BTB 2.  
Keyword
 Alternative splicing; Complete proteome; Kelch repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 837 AA 
Protein Sequence
MAGSGGPIGS GALTGGVRSK VAPSVDFDHS CSDSVEYLTL NFGPFETVHR WRRLPPCDEF 60
VGARRSKHTV VAYKDAIYVF GGDNGKTMLN DLLRFDVKDC SWCRAFTTGT PPAPRYHHSA 120
VVYGSSMFVF GGYTGDIYSN SNLKNKNDLF EYKFATGQWT EWKIEGRLPV ARSAHGATVY 180
SDKLWIFAGY DGNARLNDMW TIGLQDRELT CWEEVAQSGE IPPSCCNFPV AVCRDKMFVF 240
SGQSGAKITN NLFQFEFKDK TWTRIPTEHL LRGSPPPPQR RYGHTMVAFD RHLYVFGGAA 300
DNTLPNELHC YDVDFQTWEV VQPSSDSEVG GAEMPERASS SEDASTLTSE ERSSFKKSRD 360
VFGLDFGTTS AKQPVHLASE LPSGRLFHAA AVISDAMYIF GGTVDNNIRS GEMYRFQFSC 420
YPKCTLHEDY GRLWEGRQFC DVEFVLGEKE ECVQGHVAIV TARSRWLRRK IVQAQEWLAQ 480
KLEEDGALAP KEAPGPAVGR ARPPLLRVAI REAEARPFEV LMQFLYTDKI KYPRKGHVED 540
VLLIMDVYKL ALSFQLCRLE QLCRQYIEAS VDLQNVLVVC ESAARLQLGQ LKEHCLNFIV 600
KESHFNQVIM MKEFERLSSP LIVEIVRRKQ QPPPRTPSDQ PVDIGTSLIQ DMKAYLEGAG 660
SEFCDITLLL DGQPRPAHKA ILAARSSYFE AMFRSFMPED GQVNISIGEM VPSRQAFESM 720
LRYIYYGEVN MPPEDSLYLF AAPYYYGFYN NRLQAYCKQN LEMNVTVQNV LQILEAADKT 780
QALDMKRHCL HIIVHQFTKV RLWPQCSRSQ LSPAGLGTSW PLSTILRQPR PEQARPQEDS 840
SAHPGRLVSS SFGHLCRSLS CPRCGC 866 
Gene Ontology
  
Interpro
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ.
 IPR015915; Kelch-typ_b-propeller.
 IPR006652; Kelch_1. 
Pfam
 PF00651; BTB
 PF01344; Kelch_1 
SMART
 SM00225; BTB 
PROSITE
 PS50097; BTB 
PRINTS