CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026203
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Clathrin interactor 1 
Protein Synonyms/Alias
 MCG22297, isoform CRA_b 
Gene Name
 Clint1 
Gene Synonyms/Alias
 mCG_22297 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
122HFVDEHGKDQGINIRubiquitination[1]
190KWDEEWDKNKSAFPFacetylation[2]
190KWDEEWDKNKSAFPFubiquitination[1]
192DEEWDKNKSAFPFSDubiquitination[1]
200SAFPFSDKLGELSDKubiquitination[1]
207KLGELSDKIGSTIDDacetylation[3]
218TIDDTISKFRRKDREacetylation[2]
218TIDDTISKFRRKDREubiquitination[1]
469NVSAVLQKPNPLYHQubiquitination[1]
641ANFANFSK*******acetylation[4]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.
 Yang L, Vaitheesvaran B, Hartil K, Robinson AJ, Hoopmann MR, Eng JK, Kurland IJ, Bruce JE.
 J Proteome Res. 2011 Sep 2;10(9):4134-49. [PMID: 21728379
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 641 AA 
Protein Sequence
MLNMWKVREL VDKATNVVMN YSEIESKVRE ATNDDPWGPS GQLMGEIAKA TFMYEQFPEL 60
MNMLWSRMLK DNKKNWRRVY KSLLLLAYLI RNGSERVVTS AREHIYDLRS LENYHFVDEH 120
GKDQGINIRQ KVKELVEFAQ DDDRLREERK KAKKNKDKYV GVSSDSVGGF RYNERYDPEP 180
KSKWDEEWDK NKSAFPFSDK LGELSDKIGS TIDDTISKFR RKDREDSPER CSDSDEEKKA 240
RRGRSPKGEF KDEEETVTTK HIHITQATET TTTRHKRTAN PSKTIDLGAA AHYTGDKASP 300
DQNASTHTPQ SSAKPSVPSS KSSGDLVDLF DGSSQSAGGS ADLFGGFADF GSAAASGNFP 360
SQATSGNGDF GDWSAFNQAP SGPVASGGEL FGSAPQSAVE LISASQPALG PPPAASNSAD 420
LFDLMGSSQA TMTSSQSMNF SLMSTNTVGL GLPMSRSQPL QNVSAVLQKP NPLYHQNTDM 480
VQKSASKTLP STWSDPSVNI SLDNLLPGMQ PSKPQQPSLN TMIQQQNMQQ PLNVMTQSFG 540
AVNLSSPSNM LPVRPQTNPL LGGPMPMNMP GVMTGTMGMA PLGNSAGMSQ GMVGMNMNMG 600
MSASGMGLSG TMGMGMPSMA MPSGTVQPKQ DAFANFANFS K 641 
Gene Ontology
  
Interpro
 IPR008942; ENTH_VHS.
 IPR013809; Epsin-like_N.
 IPR001026; Epsin_dom_N. 
Pfam
 PF01417; ENTH 
SMART
 SM00273; ENTH 
PROSITE
 PS50942; ENTH 
PRINTS