UniProt Accession

 LSRG_ECOLI; P64461; P76144; Q2MB98 

Genbank Protein ID

 U00096; AP009048 

Genbank Nucleotide ID

 AAC74591.1; BAE76458.1 

Protein Name

 Autoinducer 2-degrading protein LsrG 

Protein Synonyms/Alias

 AI-2-degrading protein LsrG 

Gene Name

 lsrG 

Gene Synonyms/Alias

 yneC; b1518; JW1511 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
66	EDAVAFHKTTPHYKT	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound. 

Sequence Annotation

  

Keyword

 Complete proteome; Cytoplasm; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 96 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003824; F:catalytic activity; IDA:EcoCyc. 

Interpro

 IPR007138; Antibiotic_mOase.
 IPR011008; Dimeric_a/b-barrel. 

Pfam

 PF03992; ABM 

SMART

  

PROSITE

  

PRINTS