CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008801
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable transporter AQR1 
Protein Synonyms/Alias
  
Gene Name
 AQR1 
Gene Synonyms/Alias
 YNL065W; N2417; YNL2417W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
29HLTREYTKPDGQTKSubiquitination[1]
35TKPDGQTKSEKLNFEubiquitination[1]
38DGQTKSEKLNFEGAYubiquitination[1]
54NSHGTLSKTTTREIEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Probable transporter that confers resistance to short- chain monocarboxylic acids and quinidine. 
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 586 AA 
Protein Sequence
MSRSNSIYTE DIEMYPTHNE QHLTREYTKP DGQTKSEKLN FEGAYINSHG TLSKTTTREI 60
EGDLDSETSS HSSDDKVDPT QQITAETKAP YTLLSYGQKW GMVAILTMCG FWSSLGSPIY 120
YPALRQLEKQ FNVDENMVNV TVVVYLLFQG ISPTVSGGLA DCFGRRPIIL AGMLIYVIAS 180
IGLACAPSYG VIIFLRCIQS IGISPTIAIS SGVVGDFTLK HERGTFVGAT SGFVLLGQCF 240
GSLIGAVLTA RWDWRAIFWF LTIGCGSCFL IAFLILPETK RTIAGNLSIK PKRFINRAPI 300
FLLGPVRRRF KYDNPDYETL DPTIPKLDLS SAGKILVLPE IILSLFPSGL LFAMWTLMLS 360
SISSGLSVAP YNYHLVIIGV CYLPGGIGGL MGSFFTGRII DMYFKRKIKK FEQDKANGLI 420
PQDAEINMFK VRLVCLLPQN FLAVVAYLLF GWSIDKGWRI ESILITSFVC SYCAMSTLST 480
STTLLVDLYP TKSSTASSCF NFVRCSLSTI FMGCFAKMKA AMTVGGTFTF LCALVFFFNF 540
LMFIPMKYGM KWREDRLLKQ QRQSWLNTLA VKAKKGTKRD QNDNHN 586 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005886; C:plasma membrane; IDA:SGD.
 GO:0015238; F:drug transmembrane transporter activity; IMP:SGD.
 GO:0008028; F:monocarboxylic acid transmembrane transporter activity; IMP:SGD.
 GO:0032973; P:amino acid export; IMP:SGD. 
Interpro
 IPR011701; MFS.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF07690; MFS_1 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS