CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040517
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Pdha1l1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
77TVRRMELKADQLYKQacetylation[1]
83LKADQLYKQKIIRGFacetylation[1]
85ADQLYKQKIIRGFCHacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 390 AA 
Protein Sequence
MRKMLAAVSR VLAGAAQKPA SRVLVASRNF ANDATFEIKK CDLHRLEEGP PVTTVLTRED 60
GLKYYRMMQT VRRMELKADQ LYKQKIIRGF CHLCDGQEAC CVGLEAGINP TDHLITAYRA 120
HGFTFTRGLP VRAILAELTG RRGGCAKGKG GSMHMYAKNF YGGNGIVGPH VPLGAGIALA 180
CKYNGKDEVC LTLYGDGAAN QGQIFEAYNM AALWKLPCIF ICENNRYGMG TSVERAAAST 240
DYYKRGDFIP GLRVDGMDIL CVREATKFAA AYCRSGKGPI LMELQTYRYH GHSMSDPGVS 300
YRTREEIQEV RSKSDPIMLL KDRMVNSNLA SVEELKEIDV EVRKEIEDAA QFATADPEPP 360
LEELGYHIYS SDPPFEVRGA NQWIKFKSVS 390 
Gene Ontology
 GO:0043231; C:intracellular membrane-bounded organelle; IEA:InterPro.
 GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:InterPro. 
Interpro
 IPR001017; DH_E1.
 IPR017597; Pyrv_DH_E1_asu_subgrp-y. 
Pfam
 PF00676; E1_dh 
SMART
  
PROSITE
  
PRINTS