CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040508
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin carboxyl-terminal hydrolase 
Protein Synonyms/Alias
  
Gene Name
 Usp11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
245QHRVVVPKKGNISDLacetylation[1]
514CVGYMLKKNPVQLKEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 700 AA 
Protein Sequence
METRNKDGTW PSAQLCGMNN MPDEDEDFQG QPGICGLTNL GNTCFMNSAL QQCLSNVPQL 60
TEYFLNNRYL EELNFRNPLG MKGELAEAYA DLVKQTWSGY HRSIVPNVFK NKVGHFASQF 120
LGYQQHDSQE LLSFLLDGLH EDLNRVKKKE YVELCNGAGR PDLEVAQEAW QNHKRRNDSV 180
IVDTFHGLFK STLVCPDCGN VSVTFDPFCY LSVPLPVCSR RVLEVFFVPM DPRRKPEQHR 240
VVVPKKGNIS DLCVALSTHT SVAPDKMIVA DVFSHRFYKL YQLEDPLSGI LDRDDIFVYE 300
VTGRIEPVEG SRDDIVVPVY LRERTPSRDY NNSYYGLILF GHPLLVSVPR DRFSWEGLYN 360
ILMYRLSRYV TKPTSDDDDG DEKGDENEDE DVEDDSSSEE EKEEMSGPTD NDGTQESEQE 420
QAGTSSGVTG RCPSLLDNSL HTSQWPPRRR RKQLFTLQTV NSNGTSDRTT SPEEAQTQPY 480
IAMDWEPEMK RRYYDEVEAE GYVKHDCVGY MLKKNPVQLK ECIKLFTTVE TLEKENPWYC 540
SSCKQHQLAT KKLDLWMLPE VLIIHLKRFS FSKFSREKLD TLVQFPIRDL DFSEFVIKPK 600
NESAPDLYKY DLIAVSNHYG GMRDGHYTTF ACNKDSGQWH YFDDNSVSPV NENQIESKAA 660
YVLFYQRQDV GRRQSQTASS ETPTSPASSS TPNSDIMDVN 700 
Gene Ontology
 GO:0005634; C:nucleus; TAS:RGD.
 GO:0004197; F:cysteine-type endopeptidase activity; TAS:RGD.
 GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD. 
Interpro
 IPR018200; Pept_C19ubi-hydrolase_C_CS.
 IPR001394; Peptidase_C19. 
Pfam
 PF00443; UCH 
SMART
  
PROSITE
 PS00972; UCH_2_1
 PS00973; UCH_2_2
 PS50235; UCH_2_3 
PRINTS