CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037992
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 E3 ubiquitin-protein ligase HUWE1 
Protein Synonyms/Alias
  
Gene Name
 Huwe1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
587PQRAALLKSMLNFLKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 914 AA 
Protein Sequence
MKVDRTKLKK TPTEAPADCR ALIDKLKVCN DEQLLLELQQ IKTWNIGKCE LYHWVDLLDR 60
FDGILADAGQ TVENMSWMLV CDRPEKEQLK MLLLAVLNFT ALLIEYSFSR HLYSSIEHLT 120
TLLASSDMQV VLAVLNLLYV FSKRSNYITR LGSDKRTPLL TRLQHLAESW GGKENGFGLA 180
ECCRDLQMLK YPPSATTLHF EFYADPGAEV KIEKRTTSNT LHYIHIEQLD KISESPSEIM 240
ESLTKMYSIP KDKQMLLFTH IRLAHGFSNH RKRLQAVQAR LHAISILVYS NALQESANSI 300
LYNGLIEELV DVLQITDKQL MEIKAASLRT LTSIVHLERT PKLSSIIDCT GTASYHGFLP 360
VLVRNCIQAM IDPSMDPYPH QFATALFSFL YHLASYDAGG EALVSCGMME ALLKVIKFLG 420
DEQDQITFVT RAVRVVDLIT NLDMAAFQSH SGLSIFIYRL EHEVDLCRKE CPFVIKPKIQ 480
RPSTTQEGEE METDMDVADV TMESSPGSSI SMEHRLDVEL RASSSNSSTS ISGPGPGPGP 540
GPGPGPGPGP GPGPGPGLGP SLGPGPGPGP RPGPGVQCIP QRAALLKSML NFLKKAIQDP 600
AFSDGIRHVM DGSLPTSLKH IISNAEYYGP SLFLLATEVV TVFVFQEPSL LSSLQDNGLT 660
DVMLHALLIK DVPATREVLG SLPNVFSALC LNARGLQSFV QCQPFERLFK VLLSPDYLPA 720
MRRRRSSDPL GDTASNLGSA VDELMRHQPT LKTDATTAII KLLEEICNLG RDPKYICQKP 780
SIQKADGTTS APPPRSNHAA EEASSEDEEE EEVQAMQSFN SAQQNETEPN QQVVGTEERI 840
PIPLMDYILN VMKFVESILS NNTTDDHCQE FVNQKGLLPL VTILGLPNLP IDFPTSAACQ 900
AVAGVCKSIL VRNI 914 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR010309; E3_Ub_ligase_DUF908.
 IPR010314; E3_Ub_ligase_DUF913. 
Pfam
 PF06012; DUF908
 PF06025; DUF913 
SMART
  
PROSITE
  
PRINTS