| Tag | Content |
|---|
| CPLM ID | CPLM-017288 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | pre-mRNA 3' end processing protein WDR33 |
Protein Synonyms/Alias | WD repeat-containing protein 33; WD repeat-containing protein WDC146 |
Gene Name | Wdr33 |
Gene Synonyms/Alias | Wdc146 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 46 | QQLTFDGKRMRKAVN | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Essential for both cleavage and polyadenylation of pre- mRNA 3' ends (By similarity). |
Sequence Annotation | REPEAT 117 156 WD 1.
REPEAT 159 198 WD 2.
REPEAT 200 239 WD 3.
REPEAT 242 283 WD 4.
REPEAT 286 325 WD 5.
REPEAT 329 369 WD 6.
REPEAT 373 412 WD 7.
DOMAIN 617 769 Collagen-like.
MOD_RES 2 2 N-acetylalanine (By similarity).
MOD_RES 7 7 Phosphoserine (By similarity).
MOD_RES 46 46 N6-acetyllysine (By similarity).
MOD_RES 1204 1204 Phosphoserine (By similarity). |
Keyword | Acetylation; Collagen; Complete proteome; mRNA processing; Nucleus; Phosphoprotein; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1330 AA |
Protein Sequence | MATEIGSPPR FFHMPRFQHQ APRQLFYKRP DFAQQQAMQQ LTFDGKRMRK AVNRKTIDYN 60
PSVIKYLENR IWQRDQRDMR AIQPDAGYYN DLVPPIGMLN NPMNAVTTKF VRTSTNKVKC 120
PVFVVRWTPE GRRLVTGASS GEFTLWNGLT FNFETILQAH DSPVRAMTWS HNDMWMLTAD 180
HGGYVKYWQS NMNNVKMFQA HKEAIREASF SPTDNKFATC SDDGTVRIWD FLRCHEERIL 240
RGHGADVKCV DWHPTKGLVV SGSKDSQQPI KFWDPKTGQS LATLHAHKNT VMEVKLNLNG 300
NWLLTASRDH LCKLFDIRNL KEELQVFRGH KKEATAVAWH PVHEGLFASG GSDGSLLFWH 360
VGVEKEVGGM EMAHEGMIWS LAWHPLGHIL CSGSNDHTSK FWTRNRPGDK MRDRYNLNLL 420
PGMSEDGVEY DDLEPNSLAV IPGMGIPEQL KLAMEQEQMG KDESSEIEMT IPGLDWGMEE 480
VMQKDQKKVP QKKVPYAKPI PAQFQQAWMQ NKVPIPAPNE VLNDRKEDIK LEEKKKTQAE 540
IEQEMATLQY TNPQLLEQLK IERLAQKQAD QIQPPPSSGT PLLGPQPFSG QGPISQIPQG 600
FQQPHPSQQM PLVPQMGPPG PQGQFRAPGP QGQMGPQGPP MHQGGGGPQG FMGPQGPQGP 660
PQGLPRPQDM HGPQGMQRHP GPHGPLGPQG PPGPQGSSGP QGHMGPQGPP GPQGHIGPQG 720
PPASQGHMGP QGPPGTQGMQ GPPGPRGMQG PPHPHGIQGG PASQGIQGPL MGLNPRGMQG 780
PPGPRENQGP APQGLMIGHP PQEMRGPHPP SGLLGHGPQE MRGPQEMRGM QGPPPQGSML 840
GPPQELRGPS GSQGQQGPPQ GSLGPPPQGG MQGPPGPQGQ QNPARGPHPS QGPIPFQQQK 900
APLLGDGPRA PFNQEGQSTG PPPLIPGLGQ QGAQGRIPPL NPGQGPGPNK GDTRGPPNHH 960
LGPMSERRHE QSGGPEHGPD RGPFRGGQDC RGPPDRRGSH PDFPDDFRPD DFHPDKRFGH 1020
RLREFEGRGG PLPQEEKWRR GGPGPPFPPD HREFNEGDGR GAARGPPGAW EGRRPGDDRF 1080
PRDPDDPRFR GRREESFRRG APPRHEGRAP PRGRDNFPGP DDFGPEEGFD ASDEAARGRD 1140
LRGRGRGTPR GGSRKCLLPT PDEFPRFEGG RKPDSWDGNR EPGPGHEHFR DAPRPDHPPH 1200
DGHSPASRER SSSLQGMDMA SLPPRKRPWH DGSGTSEHRE MEAQGGPSED RGSKGRGGPG 1260
PSQRVPKSGR SSSLDGDHHD GYHRDEPFGG PPGSSSSSRG ARSGSNWGRG SNMNSGPPRR 1320
GTSRGSGRGR 1330 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |