CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027506
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Dikar, isoform C 
Protein Synonyms/Alias
 Dikar, isoform G 
Gene Name
 dikar 
Gene Synonyms/Alias
 CG32394; Dmel_CG42799 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
1780TQDFSLGKSLEEMSGacetylation[1]
3070RAALGMPKPYDINRQacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 3080 AA 
Protein Sequence
MVSTFIGLLD IQSWWEIPCI SHFCSLFSSA FDLPDIDIED LESALLSDGT SDEDQVALVP 60
ELIVRLLKGC DALQTVAKEI THSNYQMFLR RFLRQQCRLH QTENHFDTDI DFQSLPVRKR 120
LHILHDLCHF RLDSVDVQVI LSNLEADSLR VEPLGYDAKN SGYWYFYGTR LYREDKATGG 180
SASSSSGSGS GGAGASTGGA SNSKGIGSNG TVWQVICFTE EDWQNLAAKF KTSTNAKERE 240
LFNILDDNFL PKLPQLFRER ERLRRRKLLQ VRNSSRIRNI AELKARQEEE RQRRERENLY 300
QDRQNAHWLA PPQQQQQQQQ QQQQQQQQSQ QRTRRRSQST STASGISTYA SSLRRTTTTN 360
SSEFLCHRET FCLSPENDED DDDDDEALDA EQQSDQPEQQ RQQEEQPPEE EQRQEPEELL 420
AVSATDDDFR SPEAPKSQTP AELKSKSSHH HHHHHHKKKK SSKKQKKRHH RDKGRERDRE 480
HHHHHRRRHK HASEADEGED DNNNHNSNSN SNSNTNSISS NNSVQPKRRR SGQQQQHHQQ 540
AETTEPSTSL SPEDKENFCR QLQLLDTNSA AIAVATSIAD LSLPSPVAHE SETEQDEQVD 600
QPAVVEAQPP ALTSAMAPAA NVKLPGRQTN NSLSSLTGNI FIPSGSAQQQ QQQSQEPPSS 660
SSSSQSGTTT TASTVRSKKQ KAVLNSSGSS STSKMADKAD RNLSKTETTG KSKKSAAGSS 720
ASSSSSKAER ISGAYSDKSG DDFTETEEVL QIGMHKVLVY VKNHRDAWPF VDPVEEDIAP 780
RYYSIIRRPM DLLKMEDKLD SGEYHKFSEF RNDFRLIVNN CRLYNGHNNE YTEMVNNLQD 840
AFEKATKKYF DNLSDDEDDD PNLSYPAADS KMNVFREKYF SKKAKEETEK DAPGRPAVSS 900
AEEDLSEIEA EAPQKAQKRK RKEKDKRRKK KTKSKADVET DDEDMEAERE PTPPPPPPTS 960
KKSKTSKTGK EKEKDKEKEK DKDKEKDKET SSFKRGRKTK SDKSASKSSK KTKKGAKKSS 1020
ADSDPESDPS DSRESEDYSD DDHISLAKTK SLVKPTARTI AAQKKKSVPA ESKVKMPTPV 1080
KRQVKGKGKG GRKAKDDSLD SDQSDVNVKK QLPPTAAAAL AESAAELEED PDDPPPDEDE 1140
DEDSSRSRSM SPFKVDLHKK YSKSALNDDL SELLTTVKKV PTAETTKLSA RHQDEADEER 1200
SSRESDGDFK SLSNSRGSSE ERPPVAKKGK KAESSKKEKE KKGRDKDRDR DKEKDKDKSR 1260
SAKDKKSKDE SPVLVAAAEA AAVVQAELDM LLPFMDKYDV IKYRRSRAAF SGSSASNSLA 1320
PSEDSKSAIT KSNRENRKAS AKREKSPDAV ENKRGRKSKD QKRSKESDKA EKSDKASKAD 1380
TEKHSEKSKK KEEPPKVVEK AQREKSPAPV SALETIKEPP APTPIATSAS GKVKEGPAKK 1440
EPKKRPDKQM PPPPKPADKS SEKGSGKKSS SKKAAQKAGQ PQTNNNTNLE ALDVETEQTL 1500
KDINRWLEHT PRFTEFSSAS NSPSRYNLLD DFDSGIGSKL DAADFRRPVA LAAPKAELVP 1560
TKLAEALNEL VSEPKEAVSK SESESVAPTP SSVSSSCGTP PHSMHSGNSI GSTSATAASS 1620
SNCSNNSMPT PLPVAVTPTP TPAPPPLLPI PKPKEPSTTQ LILNPPPPPH IKQQLAKEAK 1680
RKSLKEKQAA QAAQAQQVKA KANVMRTIDR LQPGKAKGNL LQNVVAVKST EEGGDSHAGV 1740
NPVTTKVKEL KNALITETCE GAPKLSLGTV LKTQDFSLGK SLEEMSGKKD ANEDDRPNEE 1800
ASPKNSSPPT TPNTEAPKPF EALHELSKRG KSSEPSKSEA SQKEKPNLSA WLKAFGGPKV 1860
SKKSEDEEKQ QTPVQDLQGD SKVAPPAHSP AGDNFSLPTV MRQRKPSTGS TNSERSSFSQ 1920
DPDSPRIAID ERYGSYAAGS YTSPIGASPI GASPIMVSPK PNDDMGKPAS PYPLNGAIKV 1980
GFYQDTTTKS SPDKSCSPRE MNSPYPQYSQ HIYSSASSPN VSTPDMSGTS PYGGGNSYNP 2040
SGSEASKTPA YSSTSPLPIY DQYKQPRSQE SDYNSSMSPS TPNPHSPYQQ PQSSPYTTPQ 2100
QSQSTHPSPY HNQSPYHQQQ HSPYHPPAAQ QQQQSSQPSH SPAAHQQALS PMHSVESPAS 2160
SAATQPPTPL AQSPAEQQHS PYQQPVLSPY QQPQQQVQPP VVPPVQPSAG AQASTALGNN 2220
GYAPTHDSYQ QLQQQQRSLY NPATLINPLS TAASSTASIT KPNNDWSLNR SLLPPSITNT 2280
VNQAAQQQQQ QQQQQAGQLQ QQPQMQAAQQ QLQSTPQQQQ QQLQGTPQQQ QLQGSQQQQQ 2340
QQQQQQQLQT SQQQQQQVLG HQQQHKPKYP TYAQYQSTNA AANAAAAADA VDNLQQQQQK 2400
IAPPTYGSDM ATFMQHQMQQ PPKTDTLINP LKRPGEEIGM DYSGNAANKM QKREETPAQQ 2460
QQQQQQQQPT QNQTQSLLNK QQQMFNSFLG TMAFGKPIGN IAPDKAFEMY NRAAAMGFPK 2520
DFAKDNSCQL QQQQQQQQSP QVTTNKQQAN QQTQQQPQQQ SQQSQPHLTQ LQTALSQNYQ 2580
QQQQQTQAQK LPQQQQQQPP QQLNYQQQQA QLNHNYTAQQ QATAVPDKPP AAQSTVAAAV 2640
SESSSNMMNL PSTAHQHHLS QTHHLAAYNK PTPPPPQTYS NPLMQSMLGY AGNYFDKTMP 2700
PAAHMYSASS SAASAYGNPA QQLPGNYVPG NNNPAHQQQQ QPQQQQQQQQ QAPAVPPAEV 2760
KAPAKRGRKK KAATIAAEAA AAAAKQQQQQ QQQQQQQAQQ QQQVAAQQQH QQQQVSAQQQ 2820
QQQHQQVAAQ QQQHQAMPQY NMPQSMASAA AATNNQLQAH AQALQQGFQL YAGLKSGGVS 2880
SPVGSSAATP VNSGGSTTNQ TAADAAAISL KTSTGGMVPG SAFNFAPTPG TLGLYGDQAA 2940
AASSYLDQFR DAPNPYYMPP APAHSGTAAN PSGNAADKGQ NPLNTAAGSY PFLAAAHPSS 3000
RAAAAAAAYP FADPNSQLYQ QYLRRDDFHT RMIFNQSLLG GPAAAAAAAG YGQPPPPPSA 3060
YQRAALGMPK PYDINRQSWF 3080 
Gene Ontology
 GO:0007616; P:long-term memory; IMP:FlyBase.
 GO:0008355; P:olfactory learning; IMP:FlyBase. 
Interpro
 IPR001487; Bromodomain. 
Pfam
 PF00439; Bromodomain 
SMART
 SM00297; BROMO 
PROSITE
 PS50014; BROMODOMAIN_2 
PRINTS
 PR00503; BROMODOMAIN.