CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042144
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphorylase 
Protein Synonyms/Alias
  
Gene Name
 LOC100721433 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
290NDNFFEGKELRLKQEacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 
Functional Description
 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). 
Sequence Annotation
  
Keyword
 Carbohydrate metabolism; Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 851 AA 
Protein Sequence
MAKPLSDQEK RRQISIRGIV GVENVAELKK GFNRHLHFTL VKDRNVATTR DYFFALAHTV 60
RDHLVGRWIR TQQHYYDKCP KRVYYLSLEF YMGRTLQNTM INLGLQNACD EAIYQLGLDM 120
EELEEVEEDA GLGNGGLGRL AACFLDSMAT LGLAAYGYGI RYEYGIFNQK IRDGWQVEEA 180
DDWLRHGNPW EKARPEFMLP VHFYGRVEHT PTGAKWLDTQ VVLALPYDTP VPGYMNNTVN 240
TMRLWSARAP NDFNLRDFNV GDYIQAVLDR NLAENISRVL YPNDNFFEGK ELRLKQEYFV 300
VAATLQDVIR RFKASKFASS DNRGTVFDAF PDQVAIQLND THPALAIPEL MRIFVDIEKL 360
PWSKAWDITK KTFAYTNHTV LPEASERWPV DLVEKLLPRH LQIIYEINQK HLDRIMALFP 420
KDVDRLRRMS LIEEEGGKRV NMAHLCIVGC HAVNGVAKIH SDIVKTKVFK DFSELEPDKF 480
QNKTNGITPR RWLLLCNPGL AELIAEKIGE DYVKDLSQLT KLHSFLGDDV FLREMAKVKQ 540
ENKLKFSQYL EKEYKVKINP SSMFDVQVKR IHEYKRQLLN CLHVITMYNR IKKDPKKLFV 600
PRTVIIGGKA APGYHMAKMI IKLITSVAEV VNNDPVVGSK LKVIFLENYR VSLAEKVIPA 660
TDLSEQISTA GTEASGTGNM KFMLNGALTI GTMDGANVEM AEEAGEENLF IFGMRVDDVA 720
ALDKKGYKAK EYYEALPELK LVIDQIDNGF FSPEQPDLFK DIINMLFHHD RFKVFADYEA 780
YVKCQEKVSQ LYMNPKAWNR MVLKNIAASG KFSSDRTIKE YARDIWNMEP SDLKISLSTE 840
SSNEVNKTKG M 851 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0016208; F:AMP binding; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:Compara.
 GO:0032052; F:bile acid binding; IEA:Compara.
 GO:0008144; F:drug binding; IEA:Compara.
 GO:0008184; F:glycogen phosphorylase activity; IEA:Compara.
 GO:0002060; F:purine nucleobase binding; IEA:Compara.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0019842; F:vitamin binding; IEA:Compara.
 GO:0042593; P:glucose homeostasis; IEA:Compara.
 GO:0005977; P:glycogen metabolic process; IEA:Compara. 
Interpro
 IPR011833; Glycg_phsphrylas.
 IPR000811; Glyco_trans_35. 
Pfam
 PF00343; Phosphorylase 
SMART
  
PROSITE
 PS00102; PHOSPHORYLASE 
PRINTS