Tag | Content |
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CPLM ID | CPLM-020716 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Serine/arginine-rich splicing factor 9 |
Protein Synonyms/Alias | Splicing factor, arginine/serine-rich 9 |
Gene Name | Srsf9 |
Gene Synonyms/Alias | Sfrs9 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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37 | DLEDLFYKYGRIREI | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays a role in constitutive splicing and can modulate the selection of alternative splice sites. Represses the splicing of MAPT/Tau exon 10 (By similarity). |
Sequence Annotation | DOMAIN 15 90 RRM 1. DOMAIN 112 188 RRM 2. REGION 189 201 Interacts with SAFB1 (By similarity). MOD_RES 190 190 Phosphoserine (By similarity). MOD_RES 193 193 Phosphotyrosine (By similarity). MOD_RES 194 194 Phosphoserine (By similarity). MOD_RES 196 196 Phosphoserine (By similarity). MOD_RES 205 205 Phosphoserine. MOD_RES 209 209 Phosphoserine (By similarity). MOD_RES 212 212 Phosphoserine. MOD_RES 217 217 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome; Repeat; Repressor; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 222 AA |
Protein Sequence | MSSGWADERG GEGDGRIYVG NLPSDVREKD LEDLFYKYGR IREIELKNRH GLVPFAFVRF 60 EDPRDAEDAI YGRNGYDYGQ CRLRVEFPRT YGGRGGWPRG ARNGPPTRRS DFRVLVSGLP 120 PSGSWQDLKD HMREAGDVCY ADVQKDGMGM VEYLRKEDME YALRKLDDTK FRSHEGETSY 180 IRVYPERSTS YGYSRSRSGS RGRDSPYQSR GSPHYFSPFR PY 222 |
Gene Ontology | GO:0005730; C:nucleolus; IEA:Compara. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0003723; F:RNA binding; IEA:UniProtKB-KW. GO:0006397; P:mRNA processing; IEA:UniProtKB-KW. GO:0048025; P:negative regulation of mRNA splicing, via spliceosome; ISS:UniProtKB. GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |