UniProt Accession

 STX3_RAT; Q08849 

Genbank Protein ID

 L20820 

Genbank Nucleotide ID

 AAA03045.1 

Protein Name

 Syntaxin-3 

Protein Synonyms/Alias

  

Gene Name

 Stx3 

Gene Synonyms/Alias

 Stx3a 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
85	EQLTTEIKKRANNVR	acetylation	[1]
100	NKLKSMEKHIEEDEV	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Potentially involved in docking of synaptic vesicles at presynaptic active zones. 

Sequence Annotation

 DOMAIN 191 253 t-SNARE coiled-coil homology.  

Keyword

 Coiled coil; Complete proteome; Membrane; Neurotransmitter transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 289 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IEA:Compara.
 GO:0042582; C:azurophil granule; IEA:Compara.
 GO:0005911; C:cell-cell junction; IEA:Compara.
 GO:0030426; C:growth cone; IDA:HGNC.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IDA:BHF-UCL.
 GO:0031201; C:SNARE complex; IDA:HGNC.
 GO:0042581; C:specific granule; IEA:Compara.
 GO:0050544; F:arachidonic acid binding; IDA:HGNC.
 GO:0006944; P:cellular membrane fusion; IDA:RGD.
 GO:0034599; P:cellular response to oxidative stress; IEA:Compara.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0046907; P:intracellular transport; TAS:RGD.
 GO:0031175; P:neuron projection development; IDA:HGNC.
 GO:0016081; P:synaptic vesicle docking involved in exocytosis; TAS:RGD. 

Interpro

 IPR015708; Syntaxin-3.
 IPR006012; Syntaxin/epimorphin_CS.
 IPR006011; Syntaxin_N.
 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom. 

Pfam

 PF05739; SNARE
 PF00804; Syntaxin 

SMART

 SM00503; SynN
 SM00397; t_SNARE 

PROSITE

 PS00914; SYNTAXIN
 PS50192; T_SNARE 

PRINTS