CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038831
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Elongation factor G, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 Gfm1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
176PFLTFINKLDRMGSNacetylation[1]
194ALQQMRSKLNHNAAFacetylation[1]
707LRSCTEGKGEYTMEYacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 748 AA 
Protein Sequence
MRLLRITAGL GRGPLPRVPA ILGWQGKQAN WKTYRWCSSG SIPNEKIRNI GISAHIDSGK 60
TTLTERVLYY TGRIATMHEV KGKDGVGAVM DSMELERQRG ITIQSAATYT MWRDVNINII 120
DTPGHVDFTI EVERALRVLD GAVLVLCAVG GVQCQTMTVS RQMKRYNVPF LTFINKLDRM 180
GSNPARALQQ MRSKLNHNAA FVQIPIGLEG DFKGIIDLIE ERAIYFDGDF GQIVRYDEIP 240
ADLRAAAADH RQELIECVAN SDEQLGELFL EEKIPSVSDL KLAIRRATLS RSFTPVFLGS 300
ALKNKGVQPL LDAVLEFLPN PSEVQNYALL NQNDSKEKNK ILMNPKRDDS HPFVGLAFKL 360
EAGRFGQLTY VRNYQGELKK GSTIYNTRTG KKVRVQRLVR MHADMMEDVE EVYAGDICAL 420
FGIDCASGDT FTNKDNSDLS MESIHVPDPV ISVAMKPSNK NDLEKFSKGI ARFTREDPTF 480
KVHFDTEQGD DCVWNGRIAP IYAQRMEREY GCPCITGKPK VRLEKPLLPL CHLILHIKSS 540
RVVPASMKVI GVLEPLAPED YTKLEFSDET FGANVPKQFV PAVEKGFLDA CEKGPLSGHK 600
LSGLRFVLQD GAHHMVDSNE ISFIRAGEGA LKQALASATL CIIEPIMSVE VIAPNEFQGA 660
VFAGINRRHG VITGQDGIED YFTLYADVPL NNMFGYSTEL RSCTEGKGEY TMEYNRYQPC 720
SPSTQEELVN KYLEATGQLP VKKGKAKN 748 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0003746; F:translation elongation factor activity; IEA:InterPro.
 GO:0006184; P:GTP catabolic process; IEA:GOC. 
Interpro
 IPR000795; EF_GTP-bd_dom.
 IPR009022; EFG_III-V.
 IPR000640; EFG_V.
 IPR027417; P-loop_NTPase.
 IPR020568; Ribosomal_S5_D2-typ_fold.
 IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
 IPR005225; Small_GTP-bd_dom.
 IPR004540; Transl_elong_EFG/EF2.
 IPR005517; Transl_elong_EFG/EF2_IV.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00679; EFG_C
 PF03764; EFG_IV
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2 
SMART
 SM00838; EFG_C
 SM00889; EFG_IV 
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.