CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009198
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cysteine dioxygenase type 1 
Protein Synonyms/Alias
 Cysteine dioxygenase type I; CDO; CDO-I 
Gene Name
 Cdo1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
8MERTELLKPRTLADLubiquitination[1]
103KLLQGNLKETLFDWPubiquitination[1]
112TLFDWPDKKSNEMIKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 METAL 86 86 Iron; catalytic.
 METAL 88 88 Iron; catalytic.
 METAL 140 140 Iron; catalytic.
 CROSSLNK 93 157 3'-(S-cysteinyl)-tyrosine (Cys-Tyr).  
Keyword
 3D-structure; Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Reference proteome; Thioether bond. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 200 AA 
Protein Sequence
MERTELLKPR TLADLIRILH ELFAGDEVNV EEVQAVLEAY ESNPAEWALY AKFDQYRYTR 60
NLVDQGNGKF NLMILCWGEG HGSSIHDHTD SHCFLKLLQG NLKETLFDWP DKKSNEMIKK 120
SERTLRENQC AYINDSIGLH RVENVSHTEP AVSLHLYSPP FDTCHAFDQR TGHKNKVTMT 180
FHSKFGIRTP FTTSGSLENN 200 
Gene Ontology
 GO:0005829; C:cytosol; IDA:MGI.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0017172; F:cysteine dioxygenase activity; TAS:MGI.
 GO:0008198; F:ferrous iron binding; IEA:Compara.
 GO:0019452; P:L-cysteine catabolic process to taurine; TAS:MGI.
 GO:0007595; P:lactation; IEA:Compara.
 GO:0043200; P:response to amino acid stimulus; IEA:Compara.
 GO:0051591; P:response to cAMP; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara.
 GO:0033762; P:response to glucagon stimulus; IEA:Compara.
 GO:0051384; P:response to glucocorticoid stimulus; IEA:Compara.
 GO:0042412; P:taurine biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR010300; Cys_dOase_I.
 IPR014710; RmlC-like_jellyroll.
 IPR011051; RmlC_Cupin. 
Pfam
 PF05995; CDO_I 
SMART
  
PROSITE
  
PRINTS