UniProt Accession

 ACTBL_HUMAN; Q562R1; B2RPJ1; Q562R2; Q562S9; Q562X8 

Genbank Protein ID

 BX648504; CH471123; BC137470; BC137473; AY970384; AY970433; AY970451; AY970452 

Genbank Nucleotide ID

 EAW54967.1; AAI37471.1; AAI37474.1; AAX82193.1; AAX82242.1; AAX82259.1; AAX82260.1 

Protein Name

 Beta-actin-like protein 2 

Protein Synonyms/Alias

 Kappa-actin 

Gene Name

 ACTBL2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
51	VMVGMGQKDCYVGDE	ubiquitination	[1, 2]
62	VGDEAQSKRGVLTLK	ubiquitination	[2]
69	KRGVLTLKYPIEHGV	methylation	[3]
192	DLTDYLMKILTERGY	ubiquitination	[1]
329	APSTMKIKIIAPPER	ubiquitination	[1, 4]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510]
 [4] Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level.
 Danielsen JM, Sylvestersen KB, Bekker-Jensen S, Szklarczyk D, Poulsen JW, Horn H, Jensen LJ, Mailand N, Nielsen ML.
 Mol Cell Proteomics. 2011 Mar;10(3):M110.003590. [PMID: 21139048] 

Functional Description

 Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (By similarity). 

Sequence Annotation

 MOD_RES 45 45 Methionine sulfoxide (By similarity).  

Keyword

 ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Nucleotide-binding; Oxidation; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 376 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW. 

Interpro

 IPR004000; Actin-related.
 IPR020902; Actin/actin-like_CS.
 IPR004001; Actin_CS. 

Pfam

 PF00022; Actin 

SMART

 SM00268; ACTIN 

PROSITE

 PS00406; ACTINS_1
 PS00432; ACTINS_2
 PS01132; ACTINS_ACT_LIKE 

PRINTS

 PR00190; ACTIN.