CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013929
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Clustered mitochondria protein homolog 
Protein Synonyms/Alias
  
Gene Name
 Cluh 
Gene Synonyms/Alias
 Kiaa0664 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
175GDSGKRKKGLEMDPIubiquitination[1]
210QPQNRDWKPLQCLKVubiquitination[1]
295QISPTFKKNFAVLQKubiquitination[1]
437FDVRDHYKDFGGDVAubiquitination[1]
509YGSIDFGKTVVSHPRubiquitination[1]
529ERTSRPLKILRHRVLubiquitination[1]
632ALQLMQQKASKVETTubiquitination[1]
635LMQQKASKVETTTSLubiquitination[1]
677SSVSGLAKVKELAETubiquitination[1]
679VSGLAKVKELAETIAubiquitination[1]
793INMRYLGKVLDLVLRubiquitination[1]
812DQLDHIYKIGIGELIubiquitination[1]
876KKRNKRRKNRPPGAAubiquitination[1]
955YSFDSRHKPAFTEEDubiquitination[1]
976VVKHVNPKASDAFHFubiquitination[1]
990FFQSGQAKVQQGFLKubiquitination[1]
1172RSALQHEKEGYTIYKubiquitination[1]
1197KESSEYLKCLTQQAVubiquitination[1]
1259QKDLENLKAEVARRHubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Involved in proper cytoplasmic distribution of mitochondria (By similarity). 
Sequence Annotation
 REPEAT 980 1013 TPR 1.
 REPEAT 1022 1055 TPR 2.
 REPEAT 1106 1139 TPR 3.
 REPEAT 1148 1181 TPR 4.
 MOD_RES 279 279 Phosphoserine (By similarity).
 MOD_RES 281 281 Phosphoserine (By similarity).
 MOD_RES 655 655 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Repeat; TPR repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1315 AA 
Protein Sequence
MLLNGDCSEN LKKEEGTSEP PRENGLDEGE PGDETTGQEV IVIQDTGFSV KILAPGIEPF 60
SLQVSPQEMV QEIHQVLMDR EDTCHRTCFS LHLDGNMLDH FSELRSVEGL QEGSVLRVVE 120
EPYTVREARI HVRHVRDLLK SLDPSDAFNG VDCNSLSFLS VFTDGDLGDS GKRKKGLEMD 180
PIDCTPPEYI LPGSRERPLC PLQPQNRDWK PLQCLKVLTM SGWNPPPGNR KMHGDLMYLF 240
VITAEDRQVS ITASTRGFYL NQSTAYHFNP KPASPRFLSH SLVELLNQIS PTFKKNFAVL 300
QKKRVQRHPF ERIATPFQVY SWTAPQAEHA MDCVRAEDAY TSRLGYEEHI PGQTRDWNEE 360
LQTTRELPRK NLPERLLRER AIFKVHSDFT AAATRGAMAV IDGNVMAINP SEETKMQMFI 420
WNNIFFSLGF DVRDHYKDFG GDVAAYVAPT NDLNGVRTYN AVDVEGLYTL GTVVVDYRGY 480
RVTAQSIIPG ILERDQEQSV IYGSIDFGKT VVSHPRYLEL LERTSRPLKI LRHRVLNDRD 540
EEVELCSSVE CKGIIGNDGR HYILDLLRTF PPDLNFLPVP GEELPEECSR AGFPRTHRHK 600
LCCLRQELVD AFVEHRYLLF MKLAALQLMQ QKASKVETTT SLENGGLPSS AETKSEDSIG 660
PEAGCEEEGS SVSGLAKVKE LAETIASDDG TVDPRSREVI RNACKAVGSI SSTAFDIRFN 720
PDIFSPGVRF PESCQDEVRD QKQLLKDAAA FLLSCQIPGL VKDCTEYAVL PMDGATLAEV 780
MRQRGINMRY LGKVLDLVLR SPARDQLDHI YKIGIGELIT RSAKHIFKTY LQGVELSGLS 840
AAISHFLNCF LSSYPNPVAH LPADELLSKK RNKRRKNRPP GAADNTAWAV MTPQELWKNI 900
CHEAKNYFDF TLECDSVDQA VETYGLQKIT LLREISLKTG IQILLKEYSF DSRHKPAFTE 960
EDVLNIFPVV KHVNPKASDA FHFFQSGQAK VQQGFLKEGC ELINEALNLF NNVYGAMHVE 1020
ICACLRLLAR LHYIMGDYAE ALSNQQKAVL MSERVMGIEH PNTIQEYMHL ALYCFASSQL 1080
STALSLLYRA RYLMLLVFGE DHPEMALLDN NIGLVLHGVM EYDLSLRFLE NALAVTTKYH 1140
GPKALKVALS HHLVARVYES KAEFRSALQH EKEGYTIYKT QLGEDHEKTK ESSEYLKCLT 1200
QQAVALQRTM NEIYRNGSSA NIPPLKFTAP SMTSVLEQLN VINGILFIPL SQKDLENLKA 1260
EVARRHQLQE ANRNRDKAEE QPMAPEPEPE PERAVEDMGS PQTAKEGPSS LNLQG 1315 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0048312; P:intracellular distribution of mitochondria; IEA:InterPro. 
Interpro
 IPR027523; CLU.
 IPR025697; CLU_dom.
 IPR023231; GSKIP/TIF31_domain.
 IPR011990; TPR-like_helical. 
Pfam
 PF13236; CLU 
SMART
  
PROSITE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS