UniProt Accession

 GSTM1_BOVIN; Q9N0V4 

Genbank Protein ID

 BC102050; AF249588 

Genbank Nucleotide ID

 AAI02051.1; AAF64308.1 

Protein Name

 Glutathione S-transferase Mu 1 

Protein Synonyms/Alias

 GST class-mu 1; GSTM1-1 

Gene Name

 GSTM1 

Gene Synonyms/Alias

 GSTM 

Created Date

 July 27, 2013 

Organism

 Bos taurus (Bovine) 

NCBI Taxa ID

 9913 

Lysine Modification

Position	Peptide	Type	References
52	QWLNEKFKLGLDFPN	acetylation	[1]
83	ILRYIARKHNLCGET	acetylation	[1]
124	SPDFEKLKPGFLKEI	acetylation	[1]
182	LDAFPNLKDFISRFE	acetylation	[1]
192	ISRFEGLKKISAYMK	acetylation	[1]
211	LPGPLFMKLAVWGNK	acetylation	[1]

Reference

 [1] Acetoxy drug: protein transacetylase of buffalo liver-characterization and mass spectrometry of the acetylated protein product.
 Kohli E, Gaspari M, Raj HG, Parmar VS, Sharma SK, van der Greef J, Kumari R, Gupta G, Seema, Khurana P, Tyagi YK, Watterson AC, Olsen CE.
 Biochim Biophys Acta. 2004 Apr 8;1698(1):55-66. [PMID: 15063315] 

Functional Description

 Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Protects against the thiol-mediated metal-catalysed oxidative inactivation of enzymes. 

Sequence Annotation

 DOMAIN 2 88 GST N-terminal.
 DOMAIN 90 208 GST C-terminal.
 REGION 7 8 Glutathione binding (By similarity).
 REGION 46 50 Glutathione binding (By similarity).
 REGION 59 60 Glutathione binding (By similarity).
 REGION 72 73 Glutathione binding (By similarity).
 BINDING 116 116 Substrate (By similarity).
 MOD_RES 23 23 Phosphotyrosine (By similarity).
 MOD_RES 33 33 Phosphotyrosine (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 218 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004364; F:glutathione transferase activity; IEA:EC. 

Interpro

 IPR010987; Glutathione-S-Trfase_C-like.
 IPR004045; Glutathione_S-Trfase_N.
 IPR017933; Glutathione_S_Trfase/Cl_chnl_C.
 IPR004046; GST_C.
 IPR003081; GST_mu.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF00043; GST_C
 PF02798; GST_N 

SMART

  

PROSITE

 PS50405; GST_CTER
 PS50404; GST_NTER 

PRINTS

 PR01267; GSTRNSFRASEM.