CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025885
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MFLJ00387 protein 
Protein Synonyms/Alias
  
Gene Name
 Pink1 
Gene Synonyms/Alias
 mFLJ00387 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
145IQAIFTQKTKRVSDPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 590 AA 
Protein Sequence
VAAGSGHRAT MAVRQALGRG LQLGRALLLR FAPKPGPLFG WGKPGPAAAW GRGERPGRVV 60
SPGAQPRPVG LPLPDRYRFF RQSVAGLAAR IQRQFMVRAR GGAGPCGRAV FLAFGLGLGL 120
IEEKQAEGRR AASACQEIQA IFTQKTKRVS DPLDTRCWQG FHLEDYLIGQ AIGKGCNAAV 180
YEATMPTLPQ HLEKAKHLGL IGKGPDVVLK GADGEQAPGT PTFPFAIKMM WNISAGSSSE 240
AILSKMSQEL VPASRVALDG EYGAVTYRRS RDGPKQLAPH PNIIRVFRAF TSSVPLLPGA 300
LADYPDMLPP HYYPEGLGHG RTLFLVMKNY PCTLRQYLEE QTPSSRLATM MTLQLLEGVD 360
HLVQQGIAHR DLKSDNILVE WDSDGCPWLV ISDFGCCLAD QHVGLRLPFN SSSVERGGNG 420
SLMAPEVSTA HSGPSAVIDY SKADTWAVGA IAYEIFGLAN PFYGQGSAHL ESRSYQEAQL 480
PEIPKSVPPE ARRLVRSLLQ REASKRPSAR LAANVLHLSL WGEHLLALKN LKLDKMIAWL 540
LQQSAATLLA DRLREKSCVE TKLQMLFLAN LECEALCQAA LLLSSWRAAP 590 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016301; F:kinase activity; IDA:MGI.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
 GO:0033603; P:positive regulation of dopamine secretion; IMP:MGI.
 GO:0032226; P:positive regulation of synaptic transmission, dopaminergic; IMP:MGI. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
  
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS