UniProt Accession

 TM115_HUMAN; Q12893; A2IDB7; O14568; Q6IAY4; Q9UIX3 

Genbank Protein ID

 U09584; CR457020; AC002481; Z84492; CH471055; BC011948; BC017367 

Genbank Nucleotide ID

 AAA92281.1; CAG33301.1; AAB67308.1; CAM28372.2; EAW65115.1; AAH11948.1; AAH17367.1 

Protein Name

 Transmembrane protein 115 

Protein Synonyms/Alias

 Placental protein 6; PP6; Protein PL6 

Gene Name

 TMEM115 

Gene Synonyms/Alias

 PL6; LUCA11.2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
289	RRRQLALKALNERLK	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 MOD_RES 320 320 Phosphoserine (By similarity).  

Keyword

 Complete proteome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 351 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB. 

Interpro

 IPR013861; DUF1751_Mem_euk. 

Pfam

 PF08551; DUF1751 

SMART

  

PROSITE

  

PRINTS