UniProt Accession

 SPSY_YEAST; Q12455; D6VYE0; Q2VQW3 

Genbank Protein ID

 AF067970; Z73318; U53879; AY899255; BK006945 

Genbank Nucleotide ID

 AAC19368.1; CAA97718.1; AAB82380.1; AAX83940.1; DAA09456.1 

Protein Name

 Spermine synthase 

Protein Synonyms/Alias

 SPMSY; Spermidine aminopropyltransferase 

Gene Name

 SPE4 

Gene Synonyms/Alias

 YLR146C; L9634.5 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
21	WFREINDKSFPGQAF	ubiquitination	[1]

Reference

 [1] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269] 

Functional Description

  

Sequence Annotation

 REGION 151 152 S-adenosylmethioninamine binding (By
 ACT_SITE 174 174 Proton acceptor (By similarity).
 BINDING 44 44 S-adenosylmethioninamine (By similarity).
 BINDING 99 99 S-adenosylmethioninamine (By similarity).
 BINDING 119 119 S-adenosylmethioninamine (By similarity).
 BINDING 177 177 Spermidine (By similarity).
 MOD_RES 5 5 Phosphoserine.  

Keyword

 Complete proteome; Phosphoprotein; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 300 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0016768; F:spermine synthase activity; IMP:SGD.
 GO:0015940; P:pantothenate biosynthetic process; IMP:SGD.
 GO:0006597; P:spermine biosynthetic process; IMP:SGD. 

Interpro

 IPR001045; Spermidine/spermine_synthase. 

Pfam

 PF01564; Spermine_synth 

SMART

  

PROSITE

 PS01330; SPERMIDINE_SYNTHASE_1
 PS51006; SPERMIDINE_SYNTHASE_2 

PRINTS