| Tag | Content |
|---|
| CPLM ID | CPLM-017983 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | POC1 centriolar protein homolog B |
Protein Synonyms/Alias | Pix1; WD repeat-containing protein 51B |
Gene Name | POC1B |
Gene Synonyms/Alias | WDR51B |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 91 | VRLWIPDKRGKFSEF | ubiquitination | [1] | | 94 | WIPDKRGKFSEFKAH | ubiquitination | [1] | | 408 | CLPTTTKKKTEDMSD | ubiquitination | [1] | | 409 | LPTTTKKKTEDMSDL | ubiquitination | [1] | | 477 | LFSAVQQKS****** | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Required for ciliogenesis. |
Sequence Annotation | REPEAT 16 55 WD 1.
REPEAT 58 99 WD 2.
REPEAT 101 139 WD 3.
REPEAT 142 181 WD 4.
REPEAT 183 223 WD 5.
REPEAT 226 265 WD 6.
REPEAT 268 307 WD 7.
MOD_RES 321 321 Phosphoserine.
MOD_RES 414 414 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Cell projection; Cilium biogenesis/degradation; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 478 AA |
Protein Sequence | MASATEDPVL ERYFKGHKAA ITSLDLSPNG KQLATASWDT FLMLWNFKPH ARAYRYVGHK 60
DVVTSVQFSP HGNLLASASR DRTVRLWIPD KRGKFSEFKA HTAPVRSVDF SADGQFLATA 120
SEDKSIKVWS MYRQRFLYSL YRHTHWVRCA KFSPDGRLIV SCSEDKTIKI WDTTNKQCVN 180
NFSDSVGFAN FVDFNPSGTC IASAGSDQTV KVWDVRVNKL LQHYQVHSGG VNCISFHPSG 240
NYLITASSDG TLKILDLLEG RLIYTLQGHT GPVFTVSFSK GGELFASGGA DTQVLLWRTN 300
FDELHCKGLT KRNLKRLHFD SPPHLLDIYP RTPHPHEEKV ETVEINPKLE VIDLQISTPP 360
VMDILSFDST TTTETSGRTL PDKGEEACGY FLNPSLMSPE CLPTTTKKKT EDMSDLPCES 420
QRSIPLAVTD ALEHIMEQLN VLTQTVSILE QRLTLTEDKL KDCLENQQKL FSAVQQKS 478 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |