CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006727
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ketol-acid reductoisomerase 
Protein Synonyms/Alias
 Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacyl reductoisomerase 
Gene Name
 ilvC 
Gene Synonyms/Alias
 BSU28290 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
37HAHALNLKESGVDVIacetylation[1]
94KVYEAEIKDELTAGKacetylation[1]
279ESMKEVLKDIQNGTFacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
  
Sequence Annotation
 ACT_SITE 107 107 Potential.  
Keyword
 Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Direct protein sequencing; NADP; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 342 AA 
Protein Sequence
MVKVYYNGDI KENVLAGKTV AVIGYGSQGH AHALNLKESG VDVIVGVRQG KSFTQAQEDG 60
HKVFSVKEAA AQAEIIMVLL PDEQQQKVYE AEIKDELTAG KSLVFAHGFN VHFHQIVPPA 120
DVDVFLVAPK GPGHLVRRTY EQGAGVPALF AIYQDVTGEA RDKALAYAKG IGGARAGVLE 180
TTFKEETETD LFGEQAVLCG GLSALVKAGF ETLTEAGYQP ELAYFECLHE LKLIVDLMYE 240
EGLAGMRYSI SDTAQWGDFV SGPRVVDAKV KESMKEVLKD IQNGTFAKEW IVENQVNRPR 300
FNAINASENE HQIEVVGRKL REMMPFVKQG KKKEAVVSVA QN 342 
Gene Ontology
 GO:0050662; F:coenzyme binding; IEA:InterPro.
 GO:0004455; F:ketol-acid reductoisomerase activity; IEA:HAMAP.
 GO:0009097; P:isoleucine biosynthetic process; IEA:HAMAP.
 GO:0009099; P:valine biosynthetic process; IEA:HAMAP. 
Interpro
 IPR008927; 6-PGluconate_DH_C-like.
 IPR013023; AcH_isomrdctse.
 IPR000506; AcH_isomrdctse_C.
 IPR013328; DH_multihelical.
 IPR013116; IlvN. 
Pfam
 PF01450; IlvC
 PF07991; IlvN 
SMART
  
PROSITE
  
PRINTS