CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015715
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Proteasomal ubiquitin receptor ADRM1 homolog 
Protein Synonyms/Alias
 p42E 
Gene Name
 CG13349 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
211RTPSAPSKSGSSRSSacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
 May function as a proteasomal ubiquitin receptor. May promote the deubiquitinating activity associated with the 26S proteasome (By similarity). 
Sequence Annotation
 DOMAIN 16 124 PH.
 MOD_RES 6 6 Phosphoserine.
 MOD_RES 185 185 Phosphoserine.
 MOD_RES 196 196 Phosphothreonine.
 MOD_RES 205 205 Phosphothreonine.
 MOD_RES 207 207 Phosphoserine.
 MOD_RES 217 217 Phosphoserine.
 MOD_RES 218 218 Phosphoserine.
 MOD_RES 219 219 Phosphoserine.
 MOD_RES 367 367 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 389 AA 
Protein Sequence
MFGRQSGLGS SSNSSNLVEF RAGRMNMVGK MVHPDPRKGL VYMTQSDDGL MHFCWKDRTS 60
GKVEDDLIVF PDDFEYKRVD QCKTGRVYVL KFKSSTRRMF FWMQEPKTDK DDEQCRRINE 120
LLNNPPSAHQ RGGGGSNDGD LQYMLNNMSQ QQLMQLFGGV GQMGGLSSLL GQMNSRTPSS 180
RNTSSSGGGG ASALQTPENV SVPRTPSAPS KSGSSRSSSN VNSQVGEGAG SSVDADAPGR 240
SLNIDLSTAL PGADAINQII ADPEHVKTLI VHLPESEDVD DDRKQQIKDN ITSPQFQQAL 300
AQFSSALQSA QLGPVIKQFE LSNEAVAAAF SGNLEDFVRA LEKSLPPGAT MGGKPSASEK 360
KASDPETPTS VARDENTDPA TEKQEEKQK 389 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0005838; C:proteasome regulatory particle; IDA:FlyBase.
 GO:0061133; F:endopeptidase activator activity; ISS:UniProtKB.
 GO:0046331; P:lateral inhibition; IMP:FlyBase.
 GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:FlyBase.
 GO:0043248; P:proteasome assembly; ISS:UniProtKB. 
Interpro
 IPR006773; 26S_Psome_Ubiquitin-recp_Rpn13. 
Pfam
 PF04683; Proteasom_Rpn13 
SMART
  
PROSITE
 PS50003; PH_DOMAIN 
PRINTS