CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023927
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Trafficking protein particle complex subunit 1 
Protein Synonyms/Alias
 BET5 homolog; Multiple myeloma protein 2; MUM-2 
Gene Name
 TRAPPC1 
Gene Synonyms/Alias
 BET5; MUM2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
51SIRSFVSKMSPLDMKubiquitination[1]
58KMSPLDMKDGFLAFQubiquitination[1, 2, 3, 4]
70AFQTSRYKLHYYETPubiquitination[2, 4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
 May play a role in vesicular transport from endoplasmic reticulum to Golgi. 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Polymorphism; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 145 AA 
Protein Sequence
MTVHNLYLFD RNGVCLHYSE WHRKKQAGIP KEEEYKLMYG MLFSIRSFVS KMSPLDMKDG 60
FLAFQTSRYK LHYYETPTGI KVVMNTDLGV GPIRDVLHHI YSALYVELVV KNPLCPLGQT 120
VQSELFRSRL DSYVRSLPFF SARAG 145 
Gene Ontology
 GO:0005801; C:cis-Golgi network; IEA:InterPro.
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
 GO:0030008; C:TRAPP complex; IEA:Compara.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro. 
Interpro
 IPR011012; Longin-like_dom.
 IPR007233; Sybindin. 
Pfam
 PF04099; Sybindin 
SMART
  
PROSITE
  
PRINTS