CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022520
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 BTB/POZ domain-containing protein 7 
Protein Synonyms/Alias
  
Gene Name
 BTBD7 
Gene Synonyms/Alias
 KIAA1525 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
538EVLSDAMKRGLISTPubiquitination[1, 2]
655VPRLLIMKDMVRRLQubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
 DOMAIN 142 211 BTB 1.
 DOMAIN 247 341 BTB 2.
 MOD_RES 1119 1119 Phosphoserine (By similarity).
 LIPID 2 2 N-myristoyl glycine.  
Keyword
 Alternative splicing; Complete proteome; Lipoprotein; Myristate; Phosphoprotein; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1132 AA 
Protein Sequence
MGANASNYPH SCSPRVGGNS QAQQTFIGTS SYSQQGYGCE SKLYSLDHGH EKPQDKKKRT 60
SGLATLKKKF IKRRKSNRSA DHAKQMRELL SGWDVRDVNA LVEEYEGTSA LKELSLQASL 120
ARPEARTLQK DMADLYEYKY CTDVDLIFQE TCFPVHRAIL AARCPFFKTL LSSSPEYGAE 180
IIMDINTAGI DMPMFSALLH YLYTGEFGME DSRFQNVDIL VQLSEEFGTP NSLDVDMRGL 240
FDYMCYYDVV LSFSSDSELV EAFGGNQNCL DEELKAHKAV ISARSPFFRN LLQRRIRTGE 300
EITDRTLRTP TRIILDESII PKKYATVILH CMYTDVVDLS VLHCSPSVGS LSEVQALVAG 360
KPNMTRAEEA MELYHIALFL EFNMLAQGCE DIIAESISLD TLIAILKWSS HPYGSKWVHR 420
QALHFLCEEF SQVMTSDVFY ELSKDHLLTA IQSDYLQASE QDILKYLIKW GEHQLMKRIA 480
DREPNLLSGT AHSVNKRGVK RRDLDMEELR EILSSLLPFV RIEHILPINS EVLSDAMKRG 540
LISTPPSDML PTTEGGKSNA WLRQKNAGIY VRPRLFSPYV EEAKSVLDEM MVEQTDLVRL 600
RMVRMSNVPD TLYMVNNAVP QCCHMISHQQ ISSNQSSPPS VVANEIPVPR LLIMKDMVRR 660
LQELRHTEQV QRAYALNCGE GATVSYEIQI RVLREFGLAD AAAELLQNPH KFFPDERFGD 720
ESPLLTMRQP GRCRVNSTPP AETMFTDLDS FVAFHPPLPP PPPPYHPPAT PIHNQLKAGW 780
KQRPPSQHPS RSFSYPCNHS LFHSRTAPKA GPPPVYLPSV KAAPPDCTST AGLGRQTVAA 840
AAATTTSTAT AAAAAASEKQ VRTQPVLNDL MPDIAVGVST LSLKDRRLPE LAVDTELSQS 900
VSEAGPGPPQ HLSCIPQRHT HTSRKKHTLE QKTDTRENPQ EYPDFYDFSN AACRPSTPAL 960
SRRTPSPSQG GYFGPDLYSH NKASPSGLKS AYLPGQTSPK KQEEARREYP LSPDGHLHRQ 1020
KNEPIHLDVV EQPPQRSDFP LAAPENASTG PAHVRGRTAV ETDLTFGLTP NRPSLSACSS 1080
EAPEERSGRR LADSESLGHG AQRNTDLERE DSISRGRRSP SKPDFLYKKS AL 1132 
Gene Ontology
  
Interpro
 IPR011705; BACK.
 IPR000210; BTB/POZ-like.
 IPR011333; BTB/POZ_fold.
 IPR013069; BTB_POZ. 
Pfam
 PF07707; BACK
 PF00651; BTB 
SMART
 SM00875; BACK
 SM00225; BTB 
PROSITE
 PS50097; BTB 
PRINTS