CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001723
UniProt Accession
Genbank Protein ID
  
Genbank Nucleotide ID
  
Protein Name
 Cytochrome c 
Protein Synonyms/Alias
 Cytochrome c557 
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Crithidia oncopelti 
NCBI Taxa ID
 5657 
Lysine Modification
Position
Peptide
Type
References
4****MPPKAREPLPPmethylation[1]
83DVYLENPKKFMPGTKmethylation[1]
Reference
 [1] Update on activities at the Universal Protein Resource (UniProt) in 2013.
 e="String">UniProt Consortium.
 Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [PMID: 23161681
Functional Description
 Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. 
Sequence Annotation
 METAL 29 29 Iron (heme axial ligand).
 METAL 91 91 Iron (heme axial ligand).
 BINDING 28 28 Heme (covalent; via 1 link).
 MOD_RES 2 2 N,N-dimethylproline.
 MOD_RES 4 4 N6,N6,N6-trimethyllysine.
 MOD_RES 83 83 N6,N6,N6-trimethyllysine.  
Keyword
 Direct protein sequencing; Electron transport; Heme; Iron; Metal-binding; Methylation; Mitochondrion; Respiratory chain; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 113 AA 
Protein Sequence
MPPKAREPLP PGDAAKGEKI FKGRAAQCHT GAKGGANGVG PNLFGIVNRH SGTVEGFAYS 60
KANADSGVVW TPEVLDVYLE NPKKFMPGTK MSFAGIKKPQ ERADLIAYLE NLK 113 
Gene Ontology
 GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
 GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. 
Interpro
 IPR002327; Cyt_c_1A/1B.
 IPR009056; Cyt_c_dom.
 IPR003088; Cyt_c_I. 
Pfam
 PF00034; Cytochrom_C 
SMART
  
PROSITE
 PS51007; CYTC 
PRINTS
 PR00604; CYTCHRMECIAB.