CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018184
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat-containing protein mio 
Protein Synonyms/Alias
  
Gene Name
 Mios 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
160PDIVPMEKVRLSAGEubiquitination[1]
479HNWSGLDKQTDIQNLubiquitination[1]
769GVSGSPTKSKVTSCPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 REPEAT 58 100 WD 1.
 REPEAT 111 155 WD 2.
 REPEAT 182 221 WD 3.
 REPEAT 223 261 WD 4.
 REPEAT 265 306 WD 5.
 REPEAT 320 360 WD 6.
 REPEAT 395 437 WD 7.
 MOD_RES 766 766 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Phosphoprotein; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 875 AA 
Protein Sequence
MSGTKPDILW APHQVDRFVV CDSELSLYHV ESAVNSELKA GSLRLSEDSA ATLLSINSDT 60
PYMKCVAWYL NYDPECLLAV GQANGRVVLT SLGQDHNSKF KDLIGKEFVP KHARQCNTLA 120
WNPLDSNWLA AGLDKHRADF SVLIWDICSK YTPDIVPMEK VRLSAGEAET TLLVTKPLYE 180
LGQNDASLSL CWLPRDQKLL LAGMHRNLAI FDLRNTSQKM FVNTKAVQGV TVDPYFHDRV 240
ASFYEGQVAI WDLRKFEKPV LTLTEQPKPL TKVAWCPTRT GLLATLTRDS NIIRLYDMQH 300
TPTPIGDETE PTIIERSVQP CDNYIASFAW HPTSQNRMIV VTPNRTMSDF TVFERISLAW 360
SPITSLMWAC GRHLYECAEE ESDNSLEKDI ATKMRLRALS RYGLDTEQVW RNHILAGNED 420
PQLKSLWYTL HFMKQYTEDN DQKSPGNKGS LVYAGIKSIV KSSLGMVESS RHNWSGLDKQ 480
TDIQNLNEER ILALQLCGWI KKGTDVDVGP FLNSLVQEGE WERAAAVALF NLDIRRAIQI 540
LNEGASSEKG DLNLNVVAMA LSGYTDEKNS LWREMCSTLR LQLNNPYLCV MFAFLTSEAG 600
AYDGVLYENK VAVRDRVAFA CKFLGDAQLN KYIEKLTNEM KEAGNLEGIL LTGLTKDGVD 660
LMESYVDRTG DVQTASYCML QGSPLDVLKD ERVQYWIENY RNLLDAWRFW HKRAEFDIHR 720
SKLDPSSKPL AQVFVSCNFC GKSISYSCSS VPHQGRGFSQ YGVSGSPTKS KVTSCPGCRK 780
PLPRCALCLI NMGTPVSSCP GGSKSDEKVD LSKDKKLAQF NNWFTWCHNC RHGGHAGHML 840
SWFRDHAECP VSACTCKCMQ LDTTGNLVPA ETVQP 875 
Gene Ontology
  
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat. 
Pfam
  
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS