UniProt Accession

 D3Z7C5_MOUSE; D3Z7C5 

Genbank Protein ID

 AC117590 

Genbank Nucleotide ID

  

Protein Name

 Ski-like protein 

Protein Synonyms/Alias

  

Gene Name

 Skil 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
269	KIILEEMKEKFSMRN	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 549 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IBA:RefGenome.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0046332; F:SMAD binding; IBA:RefGenome.
 GO:0001825; P:blastocyst formation; IMP:MGI.
 GO:0007050; P:cell cycle arrest; IMP:MGI.
 GO:0070306; P:lens fiber cell differentiation; IDA:MGI.
 GO:0002260; P:lymphocyte homeostasis; IMP:MGI.
 GO:0045596; P:negative regulation of cell differentiation; IDA:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IMP:MGI.
 GO:0042981; P:regulation of apoptotic process; IMP:MGI.
 GO:0007179; P:transforming growth factor beta receptor signaling pathway; IGI:MGI. 

Interpro

 IPR014890; c-SKI_SMAD4-bd_dom.
 IPR009061; DNA-bd_dom_put.
 IPR010919; SAND_dom-like.
 IPR003380; Transform_Ski.
 IPR023216; Tscrpt_reg_SKI_SnoN. 

Pfam

 PF08782; c-SKI_SMAD_bind
 PF02437; Ski_Sno 

SMART

 SM01046; c-SKI_SMAD_bind 

PROSITE

  

PRINTS