| Tag | Content |
|---|
| CPLM ID | CPLM-022706 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Breast cancer anti-estrogen resistance protein 3 |
Protein Synonyms/Alias | p130Cas-binding protein AND-34 |
Gene Name | Bcar3 |
Gene Synonyms/Alias | And34 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 798 | NQNERYDKFNQILTA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May act as an adapter protein and couple activated growth factor receptors to signaling molecules that regulate src kinase activity and promote cell migration. |
Sequence Annotation | DOMAIN 148 247 SH2.
DOMAIN 543 813 Ras-GEF.
MOD_RES 32 32 Phosphoserine (By similarity).
MOD_RES 77 77 Phosphoserine (By similarity).
MOD_RES 176 176 Phosphoserine (By similarity).
MOD_RES 284 284 Phosphoserine (By similarity).
MOD_RES 353 353 Phosphoserine (By similarity).
MOD_RES 358 358 Phosphoserine (By similarity).
MOD_RES 365 365 Phosphoserine.
MOD_RES 370 370 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Guanine-nucleotide releasing factor; Phosphoprotein; Reference proteome; SH2 domain. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 820 AA |
Protein Sequence | MAAGKFASLP RNMPVNHQFP LASSMDLLSS KSPLAERRTD AYQDVSIHGT LPRKKKGPPS 60
IRSCDNAGHS KSPRQSSPLT QDIIQENPLQ DRKGENFIFR DPYLLDPTLE YVKFSKERHI 120
MDRTPERLKK ELEEELLLSS EDLRSHAWYH GRIPRQVSEN LVQRDGDFLV RDSLSSPGNF 180
VLTCQWKNLA QHFKINRTVL RLSEAYSRVQ YQFEMESFDS IPGLVRCYVG NRRPISQQSG 240
AIIFQPINRT VPLWCLEERY GTSPGRGREG SLAEGRPDVV KRLSLTTGSS IQAREHSLPR 300
GNLLRNKEKS GSQPACLDHV QDRKALTLKA HQSESHLPIG CKLPPQSPSM DTSPCPSSPV 360
FRTGSEPTLS PALVRRFSSD ARTGEALRGS DSQLCPKPPP KPCKVPFLKT PPSPSPWLTS 420
EANYCELNPA FAVGCDRGAK LPMQAHDSHE MLLTAKQNGP SGPRNSGINY MILDGDDQAR 480
HWDPLAVQTD EGQEDKTKFV PPLMETVSSF RPNDFESKLL PPENKPLETA MLKHAKELFT 540
NHDARVIAQH MLSVDCKVAR ILEVSEDRKR SMGVSSGLEL ITLPHGRQLR LDIIERHNTM 600
AIGIAVDILG CTGTLENRAG TLNKIIQVAV ELKDAMGDLY AFSAIMKALE MPQITRLEKT 660
WTALRHHYTQ TAILYEKQLK PFSKILHEGR ESTYVPASNV SVPLLMPLVT LMERQAVTFE 720
GTDMWENNDE SCEILLNHLA TARFMAEASE SYRMNAERIL ADFQPDEEMT EILRTEFQMR 780
LLWGSKGAEV NQNERYDKFN QILTALSRKL EPPSGKQAEL 820 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |