| Tag | Content |
|---|
| CPLM ID | CPLM-019995 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Equilibrative nucleoside transporter 3 |
Protein Synonyms/Alias | mENT3; Solute carrier family 29 member 3 |
Gene Name | Slc29a3 |
Gene Synonyms/Alias | Ent3 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 377 | QVPGPRSKLLPGLVV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine (By similarity). |
Sequence Annotation | MOD_RES 21 21 Phosphoserine.
CARBOHYD 84 84 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Endosome; Glycoprotein; Lysosome; Membrane; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 475 AA |
Protein Sequence | MAFASEDNVY HSSNAVYRAP SNHQEADQEA LLGKLLDYPA PGLQRPEDRF NGAYIIFFCL 60
GIGGLLPWNF FVTAKEYWAY KLRNCSSPAS GEDPEDMDIL NYFESYLAVA STVPSLLFLV 120
ANFLLVNRVQ VHVRVLASLS VSLAIFVVMI VLVKVDTSSW TRGFFSLTIA CMAIISSSST 180
IFNSSVYGLT GSFPMRNAQA LISGGAMGGT VSAVALLVDL AASSDVRDST LAFFLMAAVF 240
LGLCMGLYLL LSQLEYARYY MRPVAPVRVF SGEDNPSQDA PSASSVAPAS RVMHTPPLGP 300
ILKKTASLGF CAVSLYFVTA FIIPAISTNI QSMHKGTGSP WTSKFFVPLT VFLLFNFADL 360
CGRQVTAWIQ VPGPRSKLLP GLVVSRFCLV PLFLLCNYQP RSHLTKVLFQ SDIYPVLFTC 420
LLGLSNGYLS TLVLIYGPKI VPRELAEATS VVMLFYMSVG LMLGSACAAL LEHFI 475 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell. GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell. GO:0005337; F:nucleoside transmembrane transporter activity; IEA:Compara. GO:0015858; P:nucleoside transport; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |