UniProt Accession

 AT1B2_RAT; P13638 

Genbank Protein ID

 J04629; U45946; D90048 

Genbank Nucleotide ID

 AAA40782.1; AAC52918.1; BAA14101.1 

Protein Name

 Sodium/potassium-transporting ATPase subunit beta-2 

Protein Synonyms/Alias

 Sodium/potassium-dependent ATPase subunit beta-2 

Gene Name

 Atp1b2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
147	NGVLNYPKRACQFNR	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. 

Sequence Annotation

 REGION 193 290 immunoglobulin-like (By similarity).
 CARBOHYD 96 96 N-linked (GlcNAc...) (Potential).
 CARBOHYD 118 118 N-linked (GlcNAc...) (Potential).
 CARBOHYD 153 153 N-linked (GlcNAc...) (Potential).
 CARBOHYD 159 159 N-linked (GlcNAc...) (Potential).
 CARBOHYD 193 193 N-linked (GlcNAc...) (Potential).
 CARBOHYD 197 197 N-linked (GlcNAc...) (Potential).
 CARBOHYD 238 238 N-linked (GlcNAc...) (Potential).
 CARBOHYD 250 250 N-linked (GlcNAc...) (Potential).
 DISULFID 129 150 By similarity.
 DISULFID 160 177 By similarity.
 DISULFID 200 261 By similarity.  

Keyword

 Cell adhesion; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Ion transport; Membrane; Potassium; Potassium transport; Reference proteome; Signal-anchor; Sodium; Sodium transport; Sodium/potassium transport; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 290 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IDA:RGD.
 GO:0005890; C:sodium:potassium-exchanging ATPase complex; IEA:InterPro.
 GO:0005391; F:sodium:potassium-exchanging ATPase activity; IDA:RGD.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. 

Interpro

 IPR000402; Na/K_ATPase_sub_beta. 

Pfam

 PF00287; Na_K-ATPase 

SMART

  

PROSITE

 PS00390; ATPASE_NA_K_BETA_1
 PS00391; ATPASE_NA_K_BETA_2 

PRINTS