| Tag | Content |
|---|
| CPLM ID | CPLM-016239 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nebulin-related-anchoring protein |
Protein Synonyms/Alias | N-RAP |
Gene Name | NRAP |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 916 | MKVEWAKKAYGLQSD | acetylation | [1] |
|
Reference | [1] Regulation of cellular metabolism by protein lysine acetylation. Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL. Science. 2010 Feb 19;327(5968):1000-4. [ PMID: 20167786] |
Functional Description | May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix (By similarity). |
Sequence Annotation | DOMAIN 4 64 LIM zinc-binding.
REPEAT 63 97 Nebulin 1.
REPEAT 156 166 Nebulin 2.
REPEAT 175 202 Nebulin 3.
REPEAT 203 237 Nebulin 4.
REPEAT 246 273 Nebulin 5.
REPEAT 298 307 Nebulin 6.
REPEAT 316 343 Nebulin 7.
REPEAT 348 382 Nebulin 8.
REPEAT 389 417 Nebulin 9.
REPEAT 419 453 Nebulin 10.
REPEAT 487 521 Nebulin 11.
REPEAT 522 556 Nebulin 12.
REPEAT 558 592 Nebulin 13.
REPEAT 602 626 Nebulin 14.
REPEAT 627 661 Nebulin 15.
REPEAT 662 692 Nebulin 16.
REPEAT 702 724 Nebulin 17.
REPEAT 726 760 Nebulin 18.
REPEAT 761 795 Nebulin 19.
REPEAT 797 831 Nebulin 20.
REPEAT 844 869 Nebulin 21.
REPEAT 870 896 Nebulin 22.
REPEAT 901 935 Nebulin 23.
REPEAT 945 963 Nebulin 24.
REPEAT 969 1003 Nebulin 25.
REPEAT 1004 1038 Nebulin 26.
REPEAT 1040 1074 Nebulin 27.
REPEAT 1078 1112 Nebulin 28.
REPEAT 1113 1139 Nebulin 29.
REPEAT 1144 1178 Nebulin 30.
REPEAT 1183 1206 Nebulin 31.
REPEAT 1212 1246 Nebulin 32.
REPEAT 1247 1281 Nebulin 33.
REPEAT 1283 1317 Nebulin 34.
REPEAT 1321 1355 Nebulin 35.
REPEAT 1356 1390 Nebulin 36.
REPEAT 1391 1421 Nebulin 37.
REPEAT 1429 1449 Nebulin 38.
REPEAT 1455 1481 Nebulin 39.
REPEAT 1490 1524 Nebulin 40.
REPEAT 1526 1560 Nebulin 41.
REPEAT 1564 1598 Nebulin 42.
REPEAT 1599 1626 Nebulin 43.
REPEAT 1640 1664 Nebulin 44. |
Keyword | Actin-binding; Alternative splicing; Complete proteome; LIM domain; Metal-binding; Polymorphism; Reference proteome; Repeat; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1730 AA |
Protein Sequence | MNVQPCSRCG YGVYPAEKIS CIDQIWHKAC FHCEVCKMML SVNNFVSHQK KPYCHAHNPK 60
NNTFTSVYHT PLNLNVRTFP EAISGIHDQE DGEQCKSVFH WDMKSKDKEG APNRQPLANE 120
RAYWTGYGEG NAWCPGALPD PEIVRMVEAR KSLGEEYTED YEQPRGKGSF PAMITPAYQR 180
AKKANQLASQ VEYKRGHDER ISRFSTVVDT PELLRSKAGA QLQSDVRYTE DYEQQRGKGS 240
FPAMITPAYQ IAKRANELAS DVRYHQQYQK EMRGMAGPAI GAEGILTREC ADQYGQGYPE 300
EYEEHRGKGS FPAMITPAYQ NAKKAHELAS DIKYRQDFNK MKGAAHYHSL PAQDNLVLKQ 360
AQSVNKLVSE VEYKKDLESS RGHSINYCET PQFRNVSKIS KFTSDNKYKE NYQNHMRGRY 420
EGVGMDRRTL HAMKVGSLAS NVAYKADYKH DIVDYNYPAT LTPSYQTAMK LVPLKDANYR 480
QSIDKLKYSS VTDTPQIVQA KINAQQLSHV NYRADYEKNK LNYTLPQDVP QLVKAKTNAK 540
LFSEVKYKEG WEKTKGKGFE MKLDAMSLLA AKASGELASN IKYKEEYEKT KGKAMGTADS 600
RLLHSLQIAK MSSEVEYKKG FEESKTRFHL PMDMVNIRHA KKAQTLASDL DYRKKLHEYT 660
VLPEDMKTQW AKKAYGLQSE LQYKADLAWM KGVGWLTEGS LNLEQAKKAG QLVSEKNYRQ 720
RVDELKFTSV TDSSQMEHAK KSQELQSGVA YKAGNEQSVH QYTISKDEPL FLQARANAAN 780
LSEKLYKSSW ENQKAKGFEL RLDSLTFLAA KAKRDLASEV KYKEDYERSR GKLIGAKDVQ 840
GDSQMSHSLQ MSKLQSELEY KKGFEDTKSQ CHVSLDMVHL VHARKAQHLA TDVGYKTAEH 900
HFTALPTDMK VEWAKKAYGL QSDNQYRADV KWMKGMGWVA TGSLNVEQAK KAGELISEKK 960
YRQHPDALKF TSIKDTPEMV QARISYTQAV DRLYREQGEN IKHHYTPTAD LPEVLLAKLN 1020
AMNISETRYK ESWSKLRDGG YKLRLDALPF QAAKASGEII SDYKYKEAFE KMKGQMLGSR 1080
SLEDDISLAH SVYATSLQSD VNYKKGFEHS KAQFHLPLDM AALVHAKKAQ TLASNQDYKH 1140
PLPQYTSLAE DLRLSCAKKA HKLQSENLYR SDLNFMRGVA CVIPGTLEIE GRKKASELIS 1200
ESKYRQHPHS FKYTAVTDTP NLLHAKFSNQ ITNERLYKAA GEDARHEYTM TLGLPEFIRA 1260
KTNAANLSDA RYKESWRNLR AQGYKLTIEA LPFQAARASG DIASDFLYRH DFVKERGKLI 1320
GPQSVRDDPR IQHCRRMGQL QSELQYRRGA TSSQAQFHLP MDMVHLVHAK NAQALASDHD 1380
YRTQYHKFTA LPEDLKMAWA KKAHALQSEL RYKSDLIGMK GIGWLALRSP QMESAKKAGE 1440
LISETKYRKK PDSIKFTTVV DSPDLVHAKN SYMHCNERMY RSGDAESLHR YTLIPDHPDF 1500
TRARLNALHL SDKVYRNSWE QTRAGSYDFR LDAIPFQTAR ASREIASDFR YKEAFLRDRG 1560
LQIGYRSVDD DPRMKHFLNV GRLQSDNEYK KDFAKSRSQF HSSTDQPGLL QAKRSQQLAS 1620
DVHYRQPLPQ PTCDPEQLGL RHAQKAHQLQ SDVKYKSDLN LTRGVGWTPP GSYKVEMARR 1680
AAELANARGL GLQGAYRGAE AVEAGDHQSG EVNPDATEIL HVKKKKALLL 1730 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |