CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031006
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 131 
Protein Synonyms/Alias
 cDNA FLJ55106, highly similar to Transmembrane protein 131 
Gene Name
 TMEM131 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
47GLSSYQQKSISLYRGubiquitination[1, 2, 3, 4]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 322 AA 
Protein Sequence
MTLVVAAARA EKEAFVQSES IIEVLRFDDG GLLQTETTLG LSSYQQKSIS LYRGNCRPIR 60
FEPPMLDFHE QPVGMPKMEK VYLHNPSSEE TITLVSISAT TSHFHASFFQ NRKILPGGNT 120
SFDVVFLARV VGNVENTLFI NTSNHGVFTY QVFGVGVPNP YRLRPFLGAR VPVNSSFSPI 180
INIHNPHSEP LQVVEMYSSG GDLHLELPTG QQGGTRKLWE IPPYETKGVM RASFSSREAD 240
NHTAFIRIKT NASDSTEFII LPVEVEVTTA PGIYSSTEML DFGTLRTQDL PKVLNLHLLN 300
SGTKDVPITH RRQKSHLSFL GK 322 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR022113; DUF3651_TMEM131.
 IPR008962; PapD-like. 
Pfam
 PF12371; DUF3651 
SMART
  
PROSITE
  
PRINTS