UniProt Accession

 MAX_DROME; P91664; Q1LZ15; Q8SXE2; Q95S07 

Genbank Protein ID

 U77369; AE014296; AY061014; AY089690; BT025211 

Genbank Nucleotide ID

 AAB39841.1; AAF49179.1; AAL28562.1; AAL90428.1; ABF17902.1 

Protein Name

 Protein max 

Protein Synonyms/Alias

 dMax; Myc-associated factor X 

Gene Name

 Max 

Gene Synonyms/Alias

 CG9648 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
70	REAVPTLKGEKASRA	acetylation	[1]
99	RKISENQKDIEEIKR	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor. 

Sequence Annotation

 DOMAIN 39 90 bHLH.
 MOD_RES 131 131 Phosphoserine.
 MOD_RES 137 137 Phosphoserine.  

Keyword

 Activator; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 161 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IC:UniProtKB.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR011598; bHLH_dom. 

Pfam

 PF00010; HLH 

SMART

 SM00353; HLH 

PROSITE

 PS50888; BHLH 

PRINTS