CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021767
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 N-acetyltransferase 8 
Protein Synonyms/Alias
 Camello-like protein 4 
Gene Name
 Nat8 
Gene Synonyms/Alias
 Cml4 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
135KDPPLGRKQLQLFRLubiquitination[1]
155HRGQGIAKALTRTVLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Plays a role in regulation of gastrulation. 
Sequence Annotation
 DOMAIN 69 217 N-acetyltransferase.  
Keyword
 Acyltransferase; Complete proteome; Developmental protein; Gastrulation; Membrane; Reference proteome; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 227 AA 
Protein Sequence
MASFRIRQFQ ERDYKQVVDV FSRGMEEHIP TAFRHLLTLP RTLLLLAVVP LAIVLVSGSW 60
FLAVVCIFFL FLFLWFLASK PWKNYVSKCL HTDMADITKS YLSVRGSGFW VAESGGQVVG 120
TVAARPVKDP PLGRKQLQLF RLSVSSQHRG QGIAKALTRT VLQFARDQGY SDVVLVTGLL 180
QQGAVTLYYS MGFQKTGESF VDILTWLVDV SLIHFIYPLP SAQKYEL 227 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; ISA:MGI.
 GO:0005794; C:Golgi apparatus; ISA:MGI.
 GO:0016021; C:integral to membrane; NAS:UniProtKB.
 GO:0008080; F:N-acetyltransferase activity; NAS:UniProtKB.
 GO:0001702; P:gastrulation with mouth forming second; IMP:UniProtKB.
 GO:0007162; P:negative regulation of cell adhesion; ISA:MGI. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 
Pfam
 PF00583; Acetyltransf_1 
SMART
  
PROSITE
 PS51186; GNAT 
PRINTS