UniProt Accession

 BASI_RAT; P26453; Q7TNP1 

Genbank Protein ID

 X54640; X67215; AY120888 

Genbank Nucleotide ID

 CAA38452.1; CAA47655.1; AAM81604.1 

Protein Name

 Basigin 

Protein Synonyms/Alias

 Glycoprotein CE9; OX-47 antigen; CD147 

Gene Name

 Bsg 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
176	HRWMRGGKVLQEDTL	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes (By similarity). 

Sequence Annotation

 DOMAIN 138 219 Ig-like C2-type.
 DOMAIN 221 320 Ig-like V-type.
 MOD_RES 357 357 Phosphothreonine (By similarity).
 CARBOHYD 160 160 N-linked (GlcNAc...) (By similarity).
 CARBOHYD 269 269 N-linked (GlcNAc...) (By similarity).
 CARBOHYD 305 305 N-linked (GlcNAc...) (Potential).
 DISULFID 157 203 By similarity.
 DISULFID 242 304 By similarity.  

Keyword

 Alternative splicing; Cell membrane; Complete proteome; Direct protein sequencing; Disulfide bond; Glycoprotein; Immunoglobulin domain; Lectin; Mannose-binding; Membrane; Phosphoprotein; Reference proteome; Signal; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 388 AA 

Protein Sequence

Gene Ontology

 GO:0002080; C:acrosomal membrane; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
 GO:0045121; C:membrane raft; IDA:RGD.
 GO:0005739; C:mitochondrion; IDA:RGD.
 GO:0042383; C:sarcolemma; IDA:RGD.
 GO:0005537; F:mannose binding; IEA:UniProtKB-KW.
 GO:0046697; P:decidualization; IEP:RGD.
 GO:0007566; P:embryo implantation; IEP:RGD.
 GO:0042475; P:odontogenesis of dentin-containing tooth; IEP:RGD.
 GO:0051591; P:response to cAMP; IEP:RGD.
 GO:0046689; P:response to mercury ion; IEP:RGD.
 GO:0043434; P:response to peptide hormone stimulus; IEP:RGD. 

Interpro

 IPR009151; Basigin.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR003598; Ig_sub2. 

Pfam

 PF07679; I-set 

SMART

 SM00409; IG
 SM00408; IGc2 

PROSITE

 PS50835; IG_LIKE 

PRINTS