| Tag | Content |
|---|
| CPLM ID | CPLM-016602 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sentrin-specific protease 7 |
Protein Synonyms/Alias | SUMO-1-specific protease 2; Sentrin/SUMO-specific protease SENP7 |
Gene Name | Senp7 |
Gene Synonyms/Alias | Kiaa1707; Susp2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 39 | ITKLLTVKSEDVLAQ | acetylation | [1] |
|
Reference | [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y. Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [ PMID: 22826441] |
Functional Description | Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full- length SUMO proteins to their mature forms (By similarity). |
Sequence Annotation | REGION 747 1037 Protease (By similarity).
ACT_SITE 847 847 By similarity.
ACT_SITE 979 979 By similarity.
MOD_RES 434 434 Phosphoserine (By similarity).
MOD_RES 435 435 Phosphoserine (By similarity). |
Keyword | Complete proteome; Hydrolase; Phosphoprotein; Protease; Reference proteome; Thiol protease; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1037 AA |
Protein Sequence | MDRARPGRRR ASSEIVTEGK RKKSSPADLQ KITKLLTVKS EDVLAQSPLS KLRGSECWWT 60
RSLRNKVICL DHKKPKAARG CPPKGLPKRH LRVMLTNVLW TDLGREFRKT LPRKDANLCA 120
PSKVQSDSLP STSVDSIETC QRLDPLHQSL NLSERTPRVI LTDIRQTELG RKYLKIPPVT 180
EASLSDTANL KSEQLSSSSD GSLESCQSVN HHKSFLSESG PKPSRTGDVP AKEAACGGQK 240
QGDDGGVTPE MAAPHPKDFN TGNKGCDYLE EGTSNKNTSY SYSEMDHTPV SRKRKKRGRS 300
NFHDSHNSKT SLDKPTEHTK EEENDSSVSR KLEESGEDSH QDPAPPEGLA PESLESEATN 360
LRSFAAGQEP DASAASGRAS SPNKSLESSA SSEVSENSSV AVKGEALTLK EASPPGGSSE 420
ESQLLISAEP IVVSSDEEGP VEHKNSVILK LQPPHEIMSE NQGTSDPQLS ELTLGACESV 480
QVTSELFPYN PDVENISCIK SNSEMDLKLD FIFTCVYIGK IKGTPKGCVT FTKKYIKIPF 540
QVSTNEISLT VDTARLKRFG LWESKDEDHS KRSHAILFLW LSSDYLQDIQ TQLENPMLSQ 600
QSKANEFIFL ELNSSISQRE ELKLKDIMME ISTKNGNLHL SCPLPWVQAL PLFQDLSPQE 660
ISFLHYYYAS ASALPTAAGA DMKKKSVSQP SNSDTIKPTY TFLHKQSSGC YSLSITSSPE 720
EEWQEVRNTG PVQKLIVYPP PPTKGGLGVT NEDLECLEEG EFLNDVIIDF YLKYLLLEKA 780
SDELVERSHI FSSFFYKCLT RKENNLTEDN PDLSVAQRRH RRVRTWTRHI NIFNKDYIFV 840
PVNESSHWYL AVICFPWLEE AVYEDCPQTV SQQFQGQQSQ HDHKMTDNDP HTTSTVSTSA 900
EDSQSTEVNM SVPKKMCKRP CILILDSLKA ASIQNTVQNL REYLEVEWEV KRKTHREFSK 960
TNMVDLCPKV PKQDNSSDCG VYLLQYVESF FQDPIVNFEL PIHLEKWFPR HVIKTKREDI 1020
RELILKLHLQ QQKGGSC 1037 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |