CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041084
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Symplekin 
Protein Synonyms/Alias
  
Gene Name
 Sympk 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
562DAQVEAMKLGAVKRIubiquitination[1]
850LLVENCPKGAETLVTubiquitination[1]
866CLHSLTDKVPPSPELubiquitination[1]
875PPSPELVKRVRDLYHubiquitination[1]
900PVLNGLEKKEVIQALubiquitination[1]
901VLNGLEKKEVIQALPubiquitination[1]
909EVIQALPKLIKLNPIubiquitination[1]
919KLNPIVVKEVFNRLLubiquitination[1]
964CDMKSIIKATNLCFAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1288 AA 
Protein Sequence
MASSSGDSVT RRSVASQFFT QEEGPSIDGM TTSERVVDLL NQAALITNDS KITVLKQVQE 60
LIINKDPTLL DNFLDEIIAF QADKSIEVRK FVIGFIEEAC KRDIELLLKL IANLNMLLRD 120
ENVNVVKKAI LTMTQLYKVA LQWMVKSRVI SDLQEACWDM VSSMAGEIIL LLDSDNDGIR 180
THAIKFVEGL IVTLSPRMAD SEVPRRQEHD ISLDRIPRDH PYIQYNVLWE EGKAAVEQLL 240
KFMVHPAISS INLTTALGSL ANIARQRPMF MSEVIQAYET LHANLPPTLA KSQVSSVRKN 300
LKLHLLSVLK HPASLEFQAQ ITTLLVDLGT PQAEIARNMP SSKDSRKRPR DDTDSTLKKM 360
KLEPNLGEDD EDKDLEPGPS GTSKASAQIS GQSDTDITAE FLQPLLTPDN VANLVLISMV 420
YLPETMPASF QAIYTPVESA GTEAQIKHLA RLMATQMTAA GLGPGVEQTK QCKEEPKEEK 480
VVKPESVLIK RRLSVQGQAI SVVGSQSTMS PLEEEVPQAK RRPEPIIPVT QPRLAGAGGR 540
KKIFRLSDVL KPLTDAQVEA MKLGAVKRIL RAEKAVACSG AAQVRIKILA SLVTQFDSGF 600
KAEVLSFILE DVRARLDLAF AWLYQEYNAY LAAGTSGTLD KYEDCLICLL SGLQEKPDQK 660
DGIFTKVVLE APLITESALE VIRKYCEDES RAYLGMSTLG DLIFKRPSRQ FQYLHVLLDL 720
SSHEKDRVRS QALLFIKRMY EKEQLREYVE KFALNYLQLL VHPNPPSVLF GADKDTEVAA 780
PWTEETVKQC LYLYLALLPQ NHKLIHELAA VYTEAIADIK RTVLRVIEQP IRGMGMNSPE 840
LLLLVENCPK GAETLVTRCL HSLTDKVPPS PELVKRVRDL YHKRLPDVRF LIPVLNGLEK 900
KEVIQALPKL IKLNPIVVKE VFNRLLGTQH GEGNSALSPL NPGELLIALH NIDSVKCDMK 960
SIIKATNLCF AERNVYTSEV LAVVMQQLME QSPLPMLLMR TVIQSLTMYP RLGGFVMNIL 1020
ARLIMKQVWK YPKVWEGFIK CCQRTKPQSF QVILQLPPQQ LGAVFDKCPE LREPLLAHVR 1080
SFTPHQQAHI PNSIMTILEA TGKQEPEVKE APSGPLEEDD LEPLALALAP APAPAPAPAP 1140
APAPAPRPPQ DLIGLRLAQE KALKRQLEEE QKQKPTGIGA PAACVSSTPS VPAAARAGPT 1200
PAEEVMEYRE EGPECETPAI FISMDDDSGL AETTLLDSSL EGPLPKEAAA VGSSSKDERS 1260
PQNLSHAVEE ALKTSSPETR EPESKGNS 1288 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005654; C:nucleoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0006378; P:mRNA polyadenylation; IEA:Compara.
 GO:0035307; P:positive regulation of protein dephosphorylation; IEA:Compara. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR021850; DUF3453.
 IPR022075; Symplekin_C. 
Pfam
 PF11935; DUF3453
 PF12295; Symplekin_C 
SMART
  
PROSITE
  
PRINTS