UniProt Accession

 RL11_ECOLI; P0A7J7; P02409; P76778; Q2M8R9 

Genbank Protein ID

 V00339; M30610; U00006; U00096; AP009048 

Genbank Nucleotide ID

 CAA23621.1; AAA24623.1; AAC43081.1; AAC76957.1; BAE77337.1 

Protein Name

 50S ribosomal protein L11 

Protein Synonyms/Alias

  

Gene Name

 rplK 

Gene Synonyms/Alias

 relC; b3983; JW3946 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
4	****MAKKVQAYVKL	methylation	[1]
40	VNIMEFCKAFNAKTD	methylation	[1]
51	AKTDSIEKGLPIPVV	acetylation	[2, 3]
72	RSFTFVTKTPPAAVL	acetylation	[2, 3]
81	PPAAVLLKKAAGIKS	acetylation	[3]
82	PAAVLLKKAAGIKSG	acetylation	[3]
87	LKKAAGIKSGSGKPN	acetylation	[3]
92	GIKSGSGKPNKDKVG	acetylation	[3]
97	SGKPNKDKVGKISRA	acetylation	[3]
100	PNKDKVGKISRAQLQ	acetylation	[3]
113	LQEIAQTKAADMTGA	acetylation	[3]

Reference

 [1] Update on activities at the Universal Protein Resource (UniProt) in 2013.
 e="String">UniProt Consortium.
 Nucleic Acids Res. 2013 Jan;41(Database issue):D43-7. [PMID: 23161681]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [3] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. 

Sequence Annotation

 MOD_RES 2 2 N,N,N-trimethylalanine.
 MOD_RES 4 4 N6,N6,N6-trimethyllysine.
 MOD_RES 40 40 N6,N6,N6-trimethyllysine.
 MOD_RES 72 72 N6-succinyllysine.
 MOD_RES 81 81 N6-succinyllysine.  

Keyword

 3D-structure; Complete proteome; Direct protein sequencing; Methylation; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 142 AA 

Protein Sequence

Gene Ontology

 GO:0022625; C:cytosolic large ribosomal subunit; IDA:EcoCyc.
 GO:0019843; F:rRNA binding; IDA:EcoCyc.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0015968; P:stringent response; IDA:EcoCyc.
 GO:0006415; P:translational termination; IMP:EcoCyc. 

Interpro

 IPR000911; Ribosomal_L11.
 IPR006519; Ribosomal_L11_bac-typ.
 IPR020783; Ribosomal_L11_C.
 IPR020785; Ribosomal_L11_CS.
 IPR020784; Ribosomal_L11_N. 

Pfam

 PF00298; Ribosomal_L11
 PF03946; Ribosomal_L11_N 

SMART

 SM00649; RL11 

PROSITE

 PS00359; RIBOSOMAL_L11 

PRINTS