| Tag | Content |
|---|
| CPLM ID | CPLM-013290 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Kelch domain-containing protein 2 |
Protein Synonyms/Alias | Endothelial differentiation inhibitory protein TNG |
Gene Name | Klhdc2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 117 | HSRGNTNKFYMLDSR | ubiquitination | [1] | | 147 | IPPSSKDKLGVWVYK | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Represses CREB3-mediated transcription by interfering with CREB3-DNA binding (By similarity). |
Sequence Annotation | REPEAT 43 89 Kelch 1.
REPEAT 102 155 Kelch 2.
REPEAT 157 202 Kelch 3.
REPEAT 229 278 Kelch 4.
REPEAT 280 329 Kelch 5.
REPEAT 331 377 Kelch 6. |
Keyword | Complete proteome; Kelch repeat; Nucleus; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 406 AA |
Protein Sequence | MADGNEDARA EDLPGPAFEN YEAMELACPA ERSGHVAVSD GRHMFVWGGY KSNQVRGLYD 60
FYLPREELWI YNMETGRWKK INTEGDVPPS MSGSCAVCVD RVLYLFGGHH SRGNTNKFYM 120
LDSRSADRGL QWERIDCQGI PPSSKDKLGV WVYKNKLIFF GGYGYLPEDK VLGTFEFDET 180
SFWNSSHPRG WNDHVHILDT ETFAWSQPIT TGKAPSPRAA HACATVGNKG FVFGGRYRDA 240
RMNDLHYLNL DTWEWNELIP QGVCPVGRSW HSLTPVSSDH LFLFGGFTTE KQPLSDAWTY 300
CISKNEWIQF NHPYVEKPRL WHTACASDEG EVIVFGGCAN NLLVHHRAAH SNEVLIFSVQ 360
PKSLVRLSLE AVICFKEMLA NSWSCLPKHL LHSVNQRFGS NNTSGS 406 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |