CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042661
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transient receptor potential cation channel subfamily A member 1 
Protein Synonyms/Alias
  
Gene Name
 TRPA1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
355KVVQLLLKKGALFLSmethylation[1]
356VVQLLLKKGALFLSDmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
  
Keyword
 ANK repeat; Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Repeat; Transmembrane; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 916 AA 
Protein Sequence
VLLEHRTIDV NLEGENGNTA VIIACTTNNS EALQILLKKG AKPCKSNKWG CFPIHQAAFS 60
GSKECMEIIL RFGEEHGYSR QLHINFMNNG KATPLHLAVQ NGDLEMIKMC LDNGAQIDPV 120
EKGRCTAIHF AATQGATEIV KLMISSYSGS VDIVNTTDGC HETMLHRASL FDHHELADYL 180
ISVGADINKI DSEGRSPLIL ATASASWNIV NLLLSKGAQV DIKDNFGRNF LHLTVQQPYG 240
LKNLRPEFMQ MQQIKELVMD EDNDGCTPLH YACRQGGPGS VNNLLGFNVS IHSKSKDKKS 300
PLHFAASYGR INTCQRLLQD ISDTRLLNEG DLHGMTPLHL AAKNGHDKVV QLLLKKGALF 360
LSDHNGWTAL HHASMGGYTQ TMKVILDTNL KCTDRLDEDG NTALHFAARE GHAKAVALLL 420
SHNADIVLNK QQASFLHLAL HNKRKEVVLT IIRSKRWDEC LKIFSHNSPG NKCPITEMIE 480
YLPECMKVLL DFCMLHSTED KSCRDYYIEY NFKYLQCPLE FTKKTPTQDV IYEPLTALNA 540
MVQNNRIELL NHPVCKEYLL MKWLAYGFRA HMMNLGSYCL GLIPMTILVV NIKPGMAFNS 600
TGIINETSDH SEILDTTNSY LIKTCMILVF LSSIFGYCKE AGQIFQQKRN YFMDISNVLE 660
WIIYTTGIIF VLPLFVEIPA HLQWQCGAIA VYFYWMNFLL YLQRFENCGI FIVMLEVILK 720
TLLRSTVVFI FLLLAFGLSF YILLNLQDPF SSPLLSIIQT FSMMLGDINY RESFLEPYLR 780
NELAHPVLSF AQLVSFTIFV PIVLMNLLIG LAVGDIAEVQ KHASLKRIAM QVELHTSLEK 840
KLPLWFLRKV DQKSTIVYPN KPRSGGMLFH IFCFLFCTGE IRQEIPNADK SLEMEILKQK 900
YRKTTCAFVL TLIPVG 916 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005216; F:ion channel activity; IEA:InterPro. 
Interpro
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR005821; Ion_trans_dom. 
Pfam
 PF12796; Ank_2
 PF00520; Ion_trans 
SMART
 SM00248; ANK 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 
PRINTS
 PR01415; ANKYRIN.