Tag | Content |
---|
CPLM ID | CPLM-014165 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Eukaryotic translation initiation factor 4H |
Protein Synonyms/Alias | eIF-4H; Williams-Beuren syndrome chromosomal region 1 protein homolog |
Gene Name | Eif4h |
Gene Synonyms/Alias | Wbscr1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
---|
80 | VRDKDTDKFKGFCYV | acetylation | [1] | 120 | VDIAEGRKQDKGGFG | acetylation | [1] | 123 | AEGRKQDKGGFGFRK | acetylation | [1] | 214 | QRPRLQLKPRTVATP | acetylation | [1] | 245 | PREEVVQKEQE**** | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA (By similarity). |
Sequence Annotation | DOMAIN 42 118 RRM. MOD_RES 2 2 N-acetylalanine (By similarity). MOD_RES 21 21 Phosphoserine (By similarity). MOD_RES 24 24 Phosphoserine (By similarity). MOD_RES 32 32 Phosphoserine (By similarity). |
Keyword | Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Initiation factor; Phosphoprotein; Protein biosynthesis; Reference proteome; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 248 AA |
Protein Sequence | MADFDTYDDR AYSSFGGGRG SRGSAGGHGS RSQKELPTEP PYTAYVGNLP FNTVQGDIDA 60 IFKDLSIRSV RLVRDKDTDK FKGFCYVEFD EVDSLKEALT YDGALLGDRS LRVDIAEGRK 120 QDKGGFGFRK GGPDDRGMGG SREPRGGWDS RDDFSSGYRD DFLGGRGGSR PGDRRAGPPM 180 GSRFRDGPPL RGSNMDFREP TEEERAQRPR LQLKPRTVAT PLNQVANPNS AIFGGARPRE 240 EVVQKEQE 248 |
Gene Ontology | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. GO:0000166; F:nucleotide binding; IEA:InterPro. GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. GO:0048589; P:developmental growth; IEA:Compara. GO:0019953; P:sexual reproduction; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |