CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033772
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Glyceraldehyde-3-phosphate dehydrogenase 
Protein Synonyms/Alias
 MCG134295 
Gene Name
 Gapdh 
Gene Synonyms/Alias
 GAPDH; mCG_134295 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
3*****MVKVGVNGFGubiquitination[1]
59GKFNGTVKAENGKLVubiquitination[1]
64TVKAENGKLVINGKPubiquitination[1]
70GKLVINGKPITIFQEubiquitination[1]
84ERDPTNIKWGEAGAEubiquitination[1]
105GVFTTMEKAGAHLKGubiquitination[1]
137VMGVNHEKYDNSLKIubiquitination[1]
143EKYDNSLKIVSNASCubiquitination[1]
184HAITATQKTVDGPSGubiquitination[1]
192TVDGPSGKLWRDGRGubiquitination[1]
213PASTGAAKAVGKVIPubiquitination[1]
217GAAKAVGKVIPELNGubiquitination[1]
225VIPELNGKLTGMAFRubiquitination[1]
249DLTCRLEKPAKYDDIubiquitination[1]
252CRLEKPAKYDDIKKVubiquitination[1]
257PAKYDDIKKVVKQASubiquitination[1]
261DDIKKVVKQASEGPLubiquitination[1]
332LMAYMASKE******ubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 333 AA 
Protein Sequence
MVKVGVNGFG RIGRLVTRAA ICSGKVEIVA INDPFIDLNY MVYMFQYDST HGKFNGTVKA 60
ENGKLVINGK PITIFQERDP TNIKWGEAGA EYVVESTGVF TTMEKAGAHL KGGAKRVIIS 120
APSADAPMFV MGVNHEKYDN SLKIVSNASC TTNCLAPLAK VIHDNFGIVE GLMTTVHAIT 180
ATQKTVDGPS GKLWRDGRGA AQNIIPASTG AAKAVGKVIP ELNGKLTGMA FRVPTPNVSV 240
VDLTCRLEKP AKYDDIKKVV KQASEGPLKG ILGYTEDQVV SCDFNSNSHS STFDAGAGIA 300
LNDNFVKLIS WYDNEYGYSN RVVDLMAYMA SKE 333 
Gene Ontology
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
 GO:0006006; P:glucose metabolic process; IEA:InterPro. 
Interpro
 IPR020831; GlycerAld/Erythrose_P_DH.
 IPR020830; GlycerAld_3-P_DH_AS.
 IPR020829; GlycerAld_3-P_DH_cat.
 IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
 IPR006424; Glyceraldehyde-3-P_DH_1.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02800; Gp_dh_C
 PF00044; Gp_dh_N 
SMART
 SM00846; Gp_dh_N 
PROSITE
 PS00071; GAPDH 
PRINTS
 PR00078; G3PDHDRGNASE.