UniProt Accession

 LY6E_HUMAN; Q16553; B2R4X5; D3DWJ2; Q0VDE5 

Genbank Protein ID

 Z68179; U42376; U56145; U66711; AK311983; CH471162; CH471162; CH471162; BC119708; BC119709 

Genbank Nucleotide ID

 CAA92321.1; AAC50519.1; AAC50616.1; AAB07513.1; BAG34922.1; EAW82287.1; EAW82288.1; EAW82290.1; AAI19709.1; AAI19710.1 

Protein Name

 Lymphocyte antigen 6E 

Protein Synonyms/Alias

 Ly-6E; Retinoic acid-induced gene E protein; RIG-E; Stem cell antigen 2; SCA-2; Thymic shared antigen 1; TSA-1 

Gene Name

 LY6E 

Gene Synonyms/Alias

 9804; RIGE; SCA2; TSA1 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
37	KSNLYCLKPTICSDQ	ubiquitination	[1]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

 DOMAIN 21 101 UPAR/Ly6.
 LIPID 101 101 GPI-anchor amidated serine (Potential).
 CARBOHYD 99 99 N-linked (GlcNAc...) (Potential).
 DISULFID 23 48 By similarity.
 DISULFID 26 35 By similarity.
 DISULFID 41 71 By similarity.
 DISULFID 75 92 By similarity.
 DISULFID 93 98 By similarity.  

Keyword

 Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; GPI-anchor; Lipoprotein; Membrane; Reference proteome; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 131 AA 

Protein Sequence

Gene Ontology

 GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.
 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0030325; P:adrenal gland development; IEA:Compara.
 GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
 GO:0048242; P:epinephrine secretion; IEA:Compara.
 GO:0001701; P:in utero embryonic development; IEA:Compara.
 GO:0042415; P:norepinephrine metabolic process; IEA:Compara.
 GO:0035265; P:organ growth; IEA:Compara.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Compara. 

Interpro

 IPR016054; LY6_UPA_recep-like.
 IPR001526; LY6_UPAR. 

Pfam

 PF00021; UPAR_LY6 

SMART

 SM00134; LU 

PROSITE

 PS00983; LY6_UPAR 

PRINTS